Infant Bacterial Therapeutics AB
Annual Report 2024
1!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
We aim to satisfy unmet medical needs of premature
infant
SIGNIFICANT EVENTS 2024
The global Phase 3 clinical trial, “The Connection Study” for the development of the drug
candidate IBP-9414 was completed. After obtaining the results and analyzing all the data, and
after positive discussions with the FDA, the company has decided to prepare a Biologics
License Application (BLA) to obtain drug approval.
The US Patent Office approved IBT's patent application for IBP-9414.
2!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Infant Bacterial Therapeutics AB (publ)
Annual Report January 1 – December 31, 2024
Table of Contents
IBT IN BRIEF 3
IBT’S HISTORY 5
MESSAGE FROM THE CEO 7
IBT’S PIPELINE 8
DIRECTORS REPORT 16
OPERATIONS 16
SIGNIFICANT EVENTS DURING 2023 16
SIGNIFICANT EVENTS AFTER THE FISCAL YEAR 17
SELECTED FINANCIAL DATA 17
FINANCIAL DEVELOPMENT 17
RISKS AND UNCERTAINTIES 19
ENVIRONMENTAL RESPONSIBILITIES 22
SUSTAINABILITY 22
LEGAL PROCEEDINGS 22
CORPORATE GOVERNANCE 22
PUBLICATION 22
CALENDAR 22
ANNUAL GENERAL MEETING 23
BOARD OF DIRECTORS RECOMMENDATION OF APPROPRIATION OF PROFITS 23
INCOME STATEMENT 24
BALANCE SHEET 25
STATEMENT OF CHANGES IN EQUITY 26
STATEMENT OF CASH FLOWS 27
NOTES 28
FINANCIAL DEFINITIONS 47
AUDITOR´S REPORT 49
CORPORATES GOVERNANCE REPORT IBT AB 53
MANAGEMENT 63
BOARD OF DIRECTORS 64
DEDUCTION OF CERTAIN KEY FIGURES 67
SHARES 67
!
The annual report is published on the company’s homepage, www.ibtherapeutics.com and is
distributed in printed form when ordered. Orders may be placed via [email protected].
The annual report is also published in Swedish.
3!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
IBT IN BRIEF
IBT is a pharmaceutical company dedicated to the development and commercialization of drugs
for diseases affecting premature infants. After 13 years of drug development, IBT has unique
expertise in the field of drugs using live bacteria as active substances, which is an important
competitive factor for our development programs.
IBT's main focus is the drug candidate IBP-9414, a formulated bacterial strain naturally found
in human breast milk. IBP-9414 is expected to be the first product in a new class of biologics
called 'Live Biotherapeutic Products' for premature infants. The drug development of IBP-9414
is currently in its final stages for this important product.
The portfolio also includes additional drug candidates, IBP-1016, IBP-1118 and IBP-1122.
IBP-1016, for the treatment of gastroschisis, a life-threatening and rare disorder in which infants
are born with an extruded bowel. IBP-1118 to prevent retinopathy of prematurity (ROP), a
leading cause of blindness in premature infants, and IBP-1122 to eliminate vancomycin-
resistant enterococci (VRE), which cause antibiotic-resistant hospital-acquired infections.
Through the development of these medicines, IBT can address medical needs where no
adequate treatments are available.
Vision
Premature infants are the most vulnerable creatures on our planet and to survive, grow
and thrive they need intensive and specialized care. Over the past 30 years, advances in
medical care have improved the chances of survival and well-being of these vulnerable
babies, both in the immediate postnatal period and throughout their lives. However, most
existing medicines and treatments are designed for adults and not adapted for this
vulnerable patient group. Specialized treatments and preventive therapies are therefore not
sufficiently developed and there is an urgent need for medicines designed for the needs of
premature babies. IBT's vision is to become an international leader in the development of
medicines in the areas of premature infants, gastrointestinal diseases and antibiotic-
resistant hospital infections.
Mission
● IBT develops, and intends to market and sell, appropriate, safe and effective drugs that can
prevent or treat rare diseases. In terms of expertise, the company focuses on three areas:
● Gastroenterology – A well-functioning gut is essential for our survival. Poor gastrointestinal
function can also lead to stunted growth and development in children. This function is most
important for premature infants.
4!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
● Premature infants - There is a significant demand for treatment solutions for premature
infants, where IBT has established a comprehensive global network of KOLs and
institutions to address this need.
● Live bacteria as active pharmaceutical ingredients - IBT is the company closest to
registering a drug with bacteria as an active substance, also called “Live Biotherapeutic
Products”. The clinical trial with the IBP 9414 project was completed in 2024. An application
for approval is expected to be submitted in 2025.
5!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
IBT’S HISTORY
2013
IBT was founded as a subsidiary of BioGaia and started the development of IBP-9414.
IBT received orphan drug approval from the FDA for L. reuteri for the prevention of NEC in
premature infants.
2014
Pharmaceutical development to define manufacturing process for IBP-9414 started.
2015
IBT received Orphan Drug Designation from the European Commission for IBP-9414 with L.
reuteri for the prevention of NEC in preterm infants.
Approval of the IND application to initiate the safety and tolerability study was obtained from
the FDA.
2016
IBT was spun off from BioGaia and was listed on Nasdaq First North.
Rare Pediatric Disease status for IBP-9414 was obtained from the FDA.
IBT added another new indication for Gastroschisis IBP-1016
2017
IBT completed safety and tolerability study for IBP-9414, which showed a similar safety and
tolerability profile in the active and placebo groups.
EMA approved IBT's proposed pediatric clinical trial program for the development of IBP-9414.
2018
A rights issue was made which, together with a directed issue at the end of 2017, raised
approximately SEK 544 million before issue costs.
In September, trading in IBT AB B shares began on Nasdaq Stockholm, Mid Cap.
The FDA recommended measuring Sustained Feeding Tolerance (SFT) as a second primary
endpoint in the upcoming Phase III study.
2019
Distribution agreement for IBP-9414 was signed with MegaPharm Ltd. for the Israeli market and
the Palestinian Authority territory.
The Investigational New Drug (IND) application was approved in the US and the clinical trial was
approved in the UK, France, Hungary and Spain.
The first patient was enrolled in the Phase III clinical trial “The Connection Study”.
2020
Approval to conduct clinical trials in Israel, Poland and Bulgaria was obtained.
2021
IBT validated Sustained Feeding Tolerance (SFT), as agreed with the FDA.
2022
A planned safety and futility analysis was conducted without remarks.
The FDA approved IBT's Orphan Drug Designation application for a drug to prevent Retinopathy
6!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
of Prematurity (ROP).
An acquisition of a drug platform aimed at preventing antibiotic-resistant hospital infections was
negotiated.
2023
A new share issue was made, raising approximately SEK 101 million before issue costs.
The European Patent Office approved the company's patent application for L. reuteri, the patent
is IBP-9414.
A planned safety analysis and futility analysis was carried out without remarks.
IBP-1016 for gastroschisis was granted orphan drug designation.
2024
During 2024, the last patient in 'The Connection Study' was recruited and completed treatment.
The results of the study showed no significant effects on the primary endpoints but a significant
difference in the secondary endpoint, reduction in the infants deaths.
The United States Patent and Trademark Office (USPTO) approved the company's patent
application for L.reuteri, known as IBP-9414.
7!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
MESSAGE FROM THE CEO
IBT is developing the world's first drug for premature babies, designed to improve the
development of their stomach and intestines. The aim is to help children avoid a range of
serious diseases such as NEC. The clinical development program has consisted of two
studies, a Phase II study that we successfully completed in 2017 and a Phase III study, “The
Connection Study”, which was completed in 2024. That study included over 2100 babies and
nearly 100 hospitals across 10 countries, the largest randomized clinical trial ever conducted
in premature babies.
In 2024, we received the results of The Connection Study. After receiving the results, we
analyzed the data together with our experts. Our conclusion is that our drug candidate IBP-
9414 meets the requirements for a pharmaceutical product, that is, today we have
documented both IBP-9414's potency and its safety. We see that IBP-9414's safety profile is
generally very good, on par with or in some complication areas even better than placebo.
When we analyzed the causes of death of the children, it is clear that many died due to
gastrointestinal complications. The overall reduction in deaths is 27% in the group treated
with IBP-9414 compared to the placebo group. After 14 days of treatment, the risk of death is
further reduced to 46%. In order to sell our product, it must be approved by pharmaceutical
authories. During the fall, IBT has had several good discussions about our conclusions of the
study with the FDA. Based on these discussions and supported by relevant guidelines, IBT
plans to submit all clinical data to the FDA. At the same time, we continue to prepare for the
launch of IBP-9414 by finalizing the validation of the production, conducting market research
and developing a strategy for distribution partners.
Finally, I would like to thank everyone at IBT, all consultants and experts who have done a
fantastic job during the fall to find alternative paths that will hopefully lead to a rapid
registration of our drug that saves the lives of premature babies.
Stockholm March 26, 2025
Staffan Strömberg
CEO
8!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
IBT’S PIPELINE
IBP-9414
IBP-9414 contains L. reuteri as active substance, which is a human bacterial strain found
naturally in breast milk. L. reuteri is a bacterium known to have anti-inflammatory, anti-
pathogenic and beneficial effects on intestinal motility. IBP-9414 has been formulated with the
highly sensitive target population of premature infants in mind.
IBT received orphan drug designation from the FDA for L. reuteri for the prevention of NEC in
premature infants in 2013 and from the European Commission in 2015. IBT received Rare
Pediatric Disease designation for IBP-9414 from the FDA in 2016.
In June 2016, IBT started a safety and tolerability study. At the end of 2017, the results of the
study showed a similar safety and tolerability profile in both the active and placebo groups.
In November 2018, following discussions with the FDA, IBT decided to modify the protocol for
the Phase III study of IBP-9414 aimed at preventing necrotizing enterocolitis (NEC) in
premature infants. In accordance with FDA guidance, IBT modified the protocol to allow for
additional areas of treatment such as shortening the time for the infant to be able to survive on
the food the infant eats. In our clinical trial, we measured this ability called 'Sustained Feeding
Tolerance' (SFT).
The pivotal Phase III study, “The Connection Study”, was initiated in 2019 and the first patient
was enrolled in July 2019. In December 2021, a blinded evaluation was presented showing
that even a reduction in time to SFT correlates with fewer complications such as sepsis and
bronchopulmonary dysplasia, a chronic lung disease affecting premature babies.
In April 2024, the last patient was enrolled in 'The Connection Study' and in July 2024, the last
patient in the study completed treatment. In August 2024, IBT received the results of the study
and in the fall of 2024, several analyses of the results were conducted.
Our study showed a favorable treatment effect on both primary endpoints, but its results did
not reach statistical significance. However, the results showed that children dosed with IBP-
9414 had a 27% lower mortality rate. The study also showed that there were no safety
concerns associated with the treatment and no evidence that IBP-9414 caused sepsis.
IBT has discussed the effects of reduced mortality, but also NEC with the FDA. There after IBT
has had further good discussions with the FDA including the urgent need for an effective
treatment for premature babies, IBT plans to submit all clinical data from the study to the FDA
in the first half of 2025.
NEC
NEC is a leading cause of death among premature infants in neonatal intensive care units
(NICU). NEC annually kills approximately 3,700 and 1,500 infants in Europe and in the USA,
9!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
respectively. NEC has an unpredictable, spontaneous, and acute onset and major surgery is
today the only available treatment. NEC is a serious inflammatory disease of the newborn bowel
in which portions of the bowel undergo tissue death (necrosis).
NEC primarily affects premature infants and the risk to contrive NEC increases the lower the
birth weight and lower gestational age. Gestational age is defined as the duration from the first
day of the last menstruation cycle until birth.
Occurrence of NEC by estimated gestational age is as set forth in Figure 1.
Figure 1. Occurrence of NEC by gestational age (Clark et al, 2012)
The disease has a higher rate of mortality in the younger and less mature infants. Mortality in
infants who had a diagnosis of NEC by estimated gestational age is as set forth in Figure 2.
10!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Figure 2. Mortality in infants who had a diagnosis of NEC by estimated gestational age (Clark et al,
2012). The number listed outside parentheses in the table above is estimated gestational age in weeks.
The number listed within parentheses represents the number of patients with NEC within each
gestational age group.
The long-term clinical consequences for infants who survive NEC are variable and include short
bowel syndrome, parenteral nutrition-associated cholestasis, abnormal growth, and adverse
neurodevelopmental outcomes, including cerebral palsy, cognitive impairment, visual
impairment, and hearing impairment.
11!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
L. reuteri
L. reuteri is a co-evolved human bacterial strain naturally present in breast milk. L. reuteri is a
live bacteria known to be anti-inflammatory, anti-pathogenic and beneficial to gut motility.
Clinical experience phase 3 results “The Connection Study”
Our study showed a favorable treatment effect on both primary endpoints, but its results did
not reach statistical significance. However, the results showed that children dosed with IBP-
9414 had a 27% lower mortality rate. The study also showed that there were no safety
problems associated with the treatment and no evidence that IBP-9414 caused sepsis.
Looking at survival as a function of time, we see a clear effect of IBP-9414 after two weeks of
treatment. See figure 1; Y-axis shows survival and X-axis shows the number of days after the
first dose is administered.
12!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Figure 1: The survival curve starts to separate after 14 days
The overall reduction in deaths of 27% in the IBP-9414 treated group compared to the
placebo group for all preterm infants in the phase study is clinically relevant. In addition, when
examining deaths occurring after 14 days of treatment, the relative risk of death is further
reduced to 46%.
The following table shows a summary of studies with L. reuteri showing clear clinical signal for
the reduction of NEC incidence and clear clinical signal for the reduction of “feeding
intolerance episodes” or time to “full enteral feeding”.
13!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Medical Need and Market
There has been little or no progress in recent years in improving outcomes for infants affected
by NEC or complications such as sepsis or bronchopulmonary dysplasia once the disease has
already broken out. In addition, none of the current standard treatments can address the
underlying risk factors. About 20 to 40% of NEC patients need surgery. Thus, the preventive
strategies are important and the need urgent. However, so far, no such strategy has been
successful or adopted as standard treatment. Therefore, there is still a great medical need for a
preventive treatment of NEC.
NEC patients require medical care and, in many cases, surgical procedures that increase
healthcare costs and prolong hospitalization. Healthcare costs have been estimated at nearly
20% of the total cost of caring for all newborns in the United States. Infants who survive NEC are
at risk of serious lifelong secondary diseases that further impair their quality of life and impose
additional costs on the patient and society. In light of the above, preventive treatment of NEC
could be expected to reduce healthcare costs. IBT intends to demonstrate these benefits in order
to obtain support from healthcare providers, insurance companies and drug-subsidizing
authorities, to contribute to the reimbursement and subsidization of IBP-9414 for the preventive
treatment of NEC.
In 2021, an independent consulting firm was engaged to evaluate the market potential for IBP-
9414. The report showed that there is a great need for improved preventive care of NEC to
alleviate both the clinical and economic burdens. The report showed that estimated peak sales
revenue was USD 630 million per year in the US, plus Europe and the rest of the world. IBT plans
to conduct new market research in 2025 to best prepare for the launch of IBP-9414. The results
of these will guide future distribution and sales activities for IBP-9414, in addition, the commercial
production needs will be influenced by how the market receives our product and how quickly we
reach expected peak sales.
IBT's strategy for distribution partners is that the company itself will be responsible for sales and
marketing in the US while the idea is to work with partners for areas outside the US.
Intellectual Property
IBP-9414 has already granted been patents covering the active substance L. reuteri held by
BioGaia. BioGaia has granted IBT an exclusive, royalty-free license to use L. reuteri in IBT's
field of interest for the duration of the patent.
IBT has applied, and intends to apply, for patent protection for its innovations in order to
ensure adequate and effective protection of IBT's existing and future commercial position and
interests. Patent applications are typically filed in the US, EU, Japan and China, but also in
other markets where it is commercially justified for the company.
The term of patent protection for IBP-9414, which has been granted in the US, extends
through 2026 and in Europe, China and Japan through 2027, after which the patent term may
be extended in certain areas of the world, which may provide the innovation with additional
patent protection.
14!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
On February 9, 2021, IBT announced that the Japanese Patent Office decided to issue an
approval for the patent: “A method of activating lactic acid bacteria”, which covers
formulations of L. reuteri including IBP-9414, and the same was announced on January 10,
2022 for Australia. The same was announced in 2021 from the patent offices of China, Mexico,
Brazil and Hong Kong. In 2024, the US Patent Office approved IBT's patent application for
IBP-9414.
IBP-1016
Gastroschisis is a rare, life-threatening and debilitating birth abnormality in infants where the
infant is born with externalized intestines.
After the initial surgical repair, gastroschisis represents an area of significant unmet medical
need with no definitive treatment available. Post-operative management of gastroschisis is
largely aimed at overcoming the significant morbidity related to the reduction in gut motility and
consequent feeding intolerance necessitating the prolonged requirement for parenteral
nutrition. Infants suffering from gastroschisis have a greatly increased risk of sepsis and liver
cholestasis. It is common for neonates born with gastroschisis to have typically an extended
hospital stay of 1-5 months thereby causing significant burden to the healthcare system.
The active bacteria used in IBP-1016 is known to enhance gut motility and function in infants
with feeding intolerance.
IBP-1118
Retinopathy of prematurity (ROP) affects 50-70% of preterm infants weighing less than 1,500
grams at birth, which in several cases leads to blindness. Current treatments do not sufficiently
address the medical need as serious cases have increased significantly from 1,7 to 14,8 per
1,000 premature infants between 1990 and 2021.
IBT is at an early stage of investigating the possibilities of developing a drug to prevent ROP, a
growing and serious condition that often leads to blindness among prematurely born babies.
The FDA granted orphan drug designation for IBT’s product on September 20th, 2022.
The drug candidate, IBP-1118, is a dipeptide developed under the direction of Dr. Josef Neu,
professor at the University of Florida Health, Department of Pediatrics, Division of Neonatology,
and Dr. Maria Grant, professor at the University of Florida Health, Department of Endocrinology,
Diabetes, and Metabolism.
IBP-1122
Antibiotic resistance is rising to dangerous levels across the world. Hospital acquired
infections caused by vancomycin-resistant enterococci (VRE) have become a serious public
health challenge linked with the complexities of antibiotic resistance, resulting in 54,000 cases
and 5,000 deaths among hospitalized patients in the United States every year. VRE infections
are estimated to cause direct annual U.S. healthcare costs of $539M.
15!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
IBP-1122 is a bacterial strain engineered to eliminate VRE and has been developed by Drs.
Nita Salzman, Chris Kristich, and Sushma Kommineni in the departments of Pediatrics and
Microbiology & Immunology at the Medical College of Wisconsin (MCW).
IBT has secured an exclusive global license from MCW for the platform consisting of
genetically modified bacteria. Leveraging MCW’s innovation and IBT’s expertise in developing
live bacteria as active pharmaceutical ingredients is a crucial step toward alleviating the
pressure placed on hospitals by vancomycin-resistant enterococci.
16!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
DIRECTORS REPORT
The Board of Directors and CEO of Infant Bacterial Therapeutics AB (publ) (”IBT”), reg. no.
556873-8586 hereby presents the Annual Report for the financial year January 1, 2024 to
December 31, 2024.
OPERATIONS
Infant Bacterial Therapeutics AB (“IBT”) is a pharmaceutical company based in Stockholm,
whose purpose is to develop and market drugs for diseases that affect prematurely born infants
or are caused by antibiotic-resistant bacteria.
IBT's main focus is the drug candidate IBP-9414, a formulated bacterial strain naturally found
in human breast milk. IBP-9414 is expected to be the first product in a new class of biologics
called 'Live Biotherapeutic Products' for premature infants. The drug development of IBP-9414
is currently in its final stages for this important product for premature babies.
The portfolio also includes additional drug candidates, IBP-1016, IBP-1118 and IBP-1122. IBP-
1016, for the treatment of gastroschisis, a life-threatening and rare disorder in which babies are
born with an obstructed bowel. IBP-1118 to prevent retinopathy of prematurity (ROP), a leading
cause of blindness in premature babies, and IBP-1122 to eliminate vancomycin-resistant
enterococci (VRE), which cause antibiotic-resistant hospital-acquired infections.
Through the development of these medicines, IBT can address medical needs where no
adequate treatments are available.
The FDA and the European Commission have granted orphan drug status and the FDA has
granted "Rare Pediatric Disease" status to IBP-9414 for the prevention of NEC.
.
SIGNIFICANT EVENTS DURING 2024
● In April, the last patient was enrolled in the global Phase 3 clinical program, “The
Connection Study”, for the development of IBP-9414.
● In July, the last patient in The Connection Study was treated, which meant that the
clinical development program was completed.
● IBT received an approved patent application from the US Patent and Trademark Office
(USPTO) for the drug candidate IBP-9414.
● In August, IBT announced that the phase 3 study did not show significant effects on the
primary endpoints but a significant difference in the secondary endpoint, reduction of
infant deaths.
● Following further analysis of the study results and dialogue with the FDA, IBT announced
in December that it is continuing to prepare a Biologics License Application (BLA) to
obtain regulatory approval.
17!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
SIGNIFICANT EVENTS AFTER THE FISCAL YEAR
No notable events have taken place after the fiscal year.
SELECTED FINANCIAL DATA
000's
2024
Jan-Dec
2023
Jan-Dec
Net sales
-
-
Other income
4
77
Operating profit/loss
-145,343
-134,617
Result after tax
-136,905
-123,068
Total assets
239,566
351,334
Cash flow for the period
-111,120
-4,704
Cash flow per share for the period (SEK)
-8.25
-0.38
Cash
223,388
329,064
Earnings per share before and after dilution (SEK)
-10.16
-9.95
Equity per share (SEK)
12.64
22.65
Equity ratio (%)
71%
87%
FINANCIAL DEVELOPMENT
Amounts are reported in KSEK (SEK in thousands). Amounts in parenthesis refer to the same
period the previous year unless stated otherwise.
Result
The operational result amounted to KSEK -145,343 (-134,617) and the result after financial
items amounted to KSEK -136,906 (-123,068).
Result after tax amounted to KSEK -136,905 (-123,068).
Result per share prior and after dilution amounted to SEK -10.16 (-9.95).
Costs
Operational costs amounted to KSEK 150,792 (132,619) prior exchange rate effects on foreign
currency deposits, and after exchange rate effects to KSEK 145,347 (134,693).
Costs related to the completed clinical study IBP-9414 amounted to KSEK 112,544 (106,450)
prior exchange rate effects. This is mainly due to increased manufacturing costs and the work
to finalize the study and prepare for applying for market approval. Personnel costs amounted
to KSEK 23,321 (17,779). The increase is mainly due to higher bonus payments in connection
18!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
with the 2024/2027 warrant program. Other external costs amounted to KSEK 14,927 (8,390).
The increase is mainly due to increased costs for consultants and marketing costs.
Costs are reported net of exchange rate effects on foreign currency deposits. Exchange rate
effects during the reporting period amounted to KSEK 5,445 (-2,074). (Note 1, 2).
On a rolling 12-month basis, the number of employees amounted to 10 (8). The company had
9 (8) employees on the balance sheet date.
Cash flow
Cash flow for the period amounted to KSEK -111,120 (-4,704). Cash flow per share
amounted to SEK -8.25 (-0.38). The lower cash flow in 2023 was due to the rights issue
that took place in June 2023
Financial position
Prepaid expenses amounted to approximately KSEK 3,224 (9,533) and relates mainly to
manufacturing of IBP-9414, rents, insurance and IT systems.
Accrued expenses amounted to approximately MSEK 21,890 (15,334) are mainly driven by
research- and development, personnel, and consultant costs.
The company´s cash balance on December 31, 2024, amounted to KSEK 223,388 compared
to KSEK 329,064 on December 31, 2023.
The company´s shareholders equity on December 31, 2024, amounted to KSEK 170,263
compared to KSEK 305,154 on December 31, 2023. Shareholders´ equity per share on
December 31, 2024, amounted to SEK 12.64 compared to 22.65 on December 31, 2023.
The company´s equity ratio on December 31, 2024, amounted to 71% compared to 87% on
December 31, 2023.
IBT’s liquidity and capital is deemed sufficient until application for market approval.
Prospects for 2025
The development plan for IBP-9414 consisted of two clinical studies: the safety and tolerability
study and the pivotal Phase III study, “The Connection Study”. The safety and tolerability
study was completed as planned in the fourth quarter of 2017. The subsequent pivotal Phase
III study, “The Connection Study”, was completed in July 2024. The results of the study were
received in Q3 2024.
The completed pivotal phase III study aimed to document the efficacy of IBP-9414 compared
to placebo and to highlight the safety of IBP-9414. After discussing the results with the FDA in
the fall of 2024, IBP-9414 is likely to be registered as a preventive drug product that reduces
the risk of intestinal necrosis in NEC patients and reduces mortality related to gastrointestinal
complications. In light of the results of the study and the urgent need for an effective treatment
of premature babies, IBT will continue the development towards drug registration in 2025.
19!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
RISKS AND UNCERTAINTIES
Risk management and control
The Company’s Board of Directors work continually and systematically with risk assessment
to identify risks and take the necessary actions to cope with them. The internal control
environment as described in the Company Code of Conduct Report comprises mainly the
following components: control environment, risk assessment, control activities, information
and communication, as well as monitoring. For every identified significant risk, risk mitigation
actions are formulated. (See note 19 Financial Risk)
Dependent on development of one product
IBT's value is to a very large extent dependent on the success of the company's
development project IBP-9414, the granting of a marketing authorization by the US Food
and Drug Administration (“FDA”) and/or the European Medicines Agency (“EMA”). If the
development of IBP-9414 fails, IBT may focus on other projects, but there is a risk that
such projects will not succeed.
Patents and trademarks
BioGaia holds a patent on L. reuteri. BioGaia has granted IBT an exclusive license to use L.
reuteri for the development of a medical treatment for premature infants. No royalties are
payable to BioGaia on the commercialization of IBT's drug candidates. The main patent
protection for IBP-9414 is the product claim for the use of L. reuteri. This form of protection is
often referred to as 'full product protection', similar to that used by the pharmaceutical
industry for new chemical entities in the small molecule product segment. Patents that include
a product claim for the bacterial strain have been issued in most major markets. The patent
protection granted in the US is valid until June 2026 and in Europe, China and Japan until May
2027, after which the patentterm can be extended in certain areas of the world, which may
provide additional patent protection for the innovation.
IBT has also applied for additional patent protection for IBP-9414 which aims to provide
increased protection for IBP-9414 until 2036.
On February 12, 2021, the Japan Patent Office issued the patent: “A method of activating
lactic acid bacteria”, which covers formulations of IBP-9414. The patent runs until 2036.
On April 13 2021, the Patent Office of China issued the patent: “A method of activating lactic
acid bacteria”, which covers formulations of IBP-9414.The patent expires in 2036.
On September 7, 2021, the Patent Office of Mexico issued the patent: “A method of activating
lactic acid bacteria”, which covers formulations of L. reuteri including IBP-9414. The patent
expires in 2036.
20!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
On December 23, 2021, the Australian Patent Office issued the patent: “A method of
activating lactic acid bacteria”, which covers formulations of L. reuteri including IBP-9414. The
patent expires in 2036.
On February 1, 2022, the Brazilian Patent Office issued a patent for L.reuteri covering IBP-
9414. The patent expires in 2036.
On January 14, 2022, the Hong Kong Patent Office issued a patent covering formulations of L.
reuteri. The patent expires in 2036.
In 2024, the United States Patent and Trademark Office (USPTO) approved IBT's patent
application for IBP-9414. The patent expires in 2037.
In addition to patent protection, IBP-9414 will also be protected by being a biological product
and granted exclusivity through its orphan drug designation. Currently, protection for orphan
drugs and biologics in the US is 7 and 12 years respectively from market authorization. Similar
rules exist in Europe.
In the type of business that IBT conducts, there is always the risk that the company's licenses,
patents, trademarks or other intellectual property rights do not provide sufficient protection for
the company's products or that the company's rights cannot be maintained. Furthermore,
patents may be infringed, which can lead to costly litigation. The outcome of such litigation
cannot be guaranteed in advance. Negative outcomes of intellectual property disputes may
result in the losing party losing protection, being prohibited from continuing to use the relevant
right or being obliged to pay damages.
Regulatory risk
IBT develops medicinal products and is dependent on assessments and decisions by applicable
authorities. Such assessments are preceded by decisions, among other, regarding permission
to conduct clinical studies, permission to market and sell pharmaceuticals, prerequisites for
prescribing pharmaceuticals, pricing of pharmaceuticals subject to reimbursement systems,
and discounts on pharmaceuticals. It cannot be guaranteed that IBT will obtain the authoritative
decisions necessary to conduct clinical studies and receive market approval.
It cannot be excluded that national authorities may take a contrary view or act to stop the
product being sold in the applicable country, which could lead to delays or withdrawal of market
approval.
To mitigate the regulatory risks IBT involves world-leading external expertise in relation to, for
example, regulatory matters or the design of clinical studies.
21!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Production
IBT uses contract manufacturers for the production of IBP-9414, which means that the
company is dependent on external deliveries meeting agreed requirements in terms of, for
example, quantity, quality and delivery time. IBT continues to evaluate various contract
manufacturers who are able to produce IBP-9414 to secure commercial volumes.
Product liability and insurance
IBT is engaged in the development of pharmaceutical products and conducts clinical trials,
which entails risks associated with product liability. In order to mitigate such risks, IBT has
insurance coverage for products under development. However, there can be no assurance
that the insurance will provide adequate protection against claims for damages in the
event of injury caused by the Company's products or product candidates. IBT may also
fail in the future to obtain or maintain insurance coverage on acceptable terms.
The Company's insurance coverage includes commercial insurance and, until the
completion of a clinical trial, special insurance for patients participating in clinical trials.
The insurance coverage is subject to ongoing review. The company considers that the
insurance coverage is adapted to the current scope of the business.
Dependence on key persons
IBT is, to a high degree, dependent on a few key persons, both employees as well as directors.
The Company’s future earnings are affected by its ability to attract and retain qualified key
persons. In cases where one or more key persons leave the Company and the Company is not
successful in replacing such persons, this might have a negative effect on the Company’s
business, financial position and earnings.
Financial Risks
A predominant share of IBT’s development costs are commitments in foreign currencies. Should
the SEK depreciate versus the specific currency, it could have a significant impact on the
Company’s financial position and results. The currencies against which IBT has the greatest
exposure are USD and EUR.
IBT’s balance sheet item “cash and cash equivalents” in the balance sheet represents cash
deposits at Swedish banks were the counterpart risk is very low. See note 19 for further
information about financial risks.
The general macroeconomic situation regarding inflation, cost increases and possible customs
charges contributes to some uncertainty and it cannot be excluded that IBT will be affected by
this in the future. So far, IBT has countered cost increases by purchasing USD and EUR in the
past when the exchange rate was more favorable.
22!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
ENVIRONMENTAL RESPONSIBILITIES
The Company’s operations do not have any specific environmental risks and is not subject to
notification obligations under the Swedish Environmental Code. The Board of Directors of the
Company is of the opinion that the Company is in compliance with applicable rules and
regulations and offers its employees a sound and safe working environment.
SUSTAINABILITY
IBT should be perceived as an innovative and creative Company that represents quality, health
and provides a function in society. It is important for IBT to work actively with sustainability
issues. Respect for human rights, environment and anti-corruption shall reflect the company’s
operations with regard to business strategies, financing, investments and purchasing
processes.
The Company is not legally required to publish a sustainability report.
LEGAL PROCEEDINGS
Provisions for litigation are based on the type of dispute and the progress of the legal process.
Furthermore, the opinions of internal and external legal and other advisors on the outcome of
the litigation are taken into account.
CORPORATE GOVERNANCE
The company’s Corporate Governance Report for 2024 is included in this annual report and
published on the Company’s webpage www.ibtherapeutics.com
PUBLICATION
IBT strives to have good communication with the Company’s shareholders. The Company’s
publication of information should be correct, pertinent, and timely. The Company’s
communication will also be characterized by openness and the Company will publish periodic
interim reports and annual reports in Swedish and English. Events which are determined to have
potential impact on the share price will be distributed as a press release.
CALENDAR
Interim report January – March 2025 May 7, 2025
Interim report January – June 2025 August 20, 2025
Interim report January – September 2025 November 13, 2025
Financial report January – December 2025 February 6, 2026
23!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
ANNUAL GENERAL MEETING
The Annual General Meeting for IBT will be held on May 8, 2025 at 16:00 CET in Stockholm.
BOARD OF DIRECTORS RECOMMENDATION OF APPROPRIATION OF PROFITS
SEK
2024
Recommendation of appropriation of profits or loss
The Board of directors propose that the following surplus:
Income carried forward
-465,346,337
Surplus reserve
768,841,897
Result for the period
-136,904,518
Total
166,591,042
To be appropriated as follows:
Income carried forward
166,591,042
Total
166,591,042
Regarding results and financial position in general please refer to the following income
statements and balance sheets with accompanying notes.
24!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
INCOME STATEMENT
SEK 000 Note
2024
Jan-Dec
2023
Jan-Dec
Net sales
-
-
Other income
4
77
Research and development costs 5
-126,051
-121,183
Administration cost. 2,3,4,5
-19,296
-13,511
Operating loss
-145,343
-134,617
Result from financial items
Interest income and similar profit/loss items
8,438
11,549
Interest expense and similar profit/loss items
-
-
Result after financial items
-136,905
-123,068
Result for the period*
-136,905
-123,068
*The result corresponds to company´s total profits
Result per share
SEK
Result per share,
before and after dilution
-10.16
-9.95
Number of shares, at beginning of period*
13,471,420
11,226,184
Number of shares, weighted average**
13,471,420
12,364,614
Number of shares at end of period ***
13 471 420
13,471,420
* As of January 1, 2023, the distribution of issued shares was 377,736 of class A shares with a voting
value of 10 and 10,848,448 of class B shares with a voting value of 1.
** Through a new share issue, the number of shares in the company was increased on July 4, 2023,
with 75,547 shares of class A and 2,169,689 shares of class B.
*** As of December 31, 2024, the distribution of issued shares is 453,283 of class A shares with voting
rights of 10 and 13,018,137 of class B shares with voting rights of 1.
25!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
BALANCE SHEET
SEK 000
Note
2024-12-31
2023-12-31
ASSETS
Non-current assets
Intangible non-current assets
Activated development costs
7
8,886
9,702
Shares in subsidiary
8
70
70
Total non-current assets
8,956
9,772
Current assets
Current receivables
Other receivables
9
3,997
2,966
Prepaid expenses and accrued income 10
3,224
9,533
Total current assets
7,221
12,499
Cash and cash equivalents
11
223,388
329 064
Total current assets
230,610
341,563
TOTAL ASSETS
239,566
351,334
EQUITY AND LIABILITIES
Equity
Restricted equity
Share capital
3,672
3 672
Unrestricted equity
Share premium reserve
768,842
766,829
Accumulated losses
-465,346
-342,280
Net loss for the year
-136,905
-123,068
Total equity
170,263
305,154
Liabilities
Current liabilities
Accounts payable
46,993
30,067
Other current liabilities
421
779
Accrued expenses and prepaid income 12
21,890
15,334
Total current liabilities
69,303
46,180
TOTAL EQUITY AND LIABILITIES
239,566
351,334
26!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
STATEMENT OF CHANGES IN EQUITY
SEK 000
Restricted equity
Unrestricted equity
Share capital
Share premium
reserve
Accumulate
d losses incl.
loss for the
period
Total
equity
Opening equity on Jan 1,
2023
3,060
670,926
-342,279
331,705
Result for the period
-123,068
-123,068
Total comprehensive income
-123,068
-123,068
Shareholder transactions
New Issue
612
100,424
101,036
Issuing cost
-5,030
-5,030
Warrants
510
510
Closing equity on Dec 31,
2023
3,672
766,830
-465,348
305,154
Opening equity on Jan 1,
2024
3,672
766,830
-465,348
305,154
Result for the period
-136,905
-136,905
Total comprehensive income
-136,905
-136,905
Shareholder transactions
Warrants
2,013
2,013
Closing equity on Dec 31,
2024
3,672
768,843
-602,252
170,263
27!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
STATEMENT OF CASH FLOWS
SEK 000
2024
Jan-Dec
2023
Jan-Dec
Operating activities
Operating profit/loss
-145,343
-134,617
Interest income received
8,438
11,549
Paid interest costs
-
-
Adjustment for non - cash flow affecting items:
Depreciation production process
816
816
Unrealized exchange rate difference in cash
5,445
2,074
Cash flow from operating activities before changes in
working capital
-141,533
-120,178
Cash flow from changes in working capital
Increase (-)/Decrease (+) in operating receivables
5,277
-9,308
Increase (+)/Decrease (-) in operating liabilities
23,123
28,267
Cash flow from operating activities
-113,133
-101,219
Investment activities
Shareholder contributions IBT Baby AB
-
-
Financing activities
New issue
-
101,036
Issuing cost
-
-5,030
Warrants
2,013
510
Cash flow from financing activities
2,013
96,515
Cash flow for the period
-111,120
-4,704
Value variance currency accounts
5,445
2,074
Cash and cash equivalents at the beginning of the period
329,064
335,840
CASH AND CASH EQUIVALENTS AT THE END OF THE YEAR
223,388
329,064
28!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
NOTES
Note 1 Accounting principles
This financial report is prepared in accordance with the Annual Accounts Act,
“Årsredovisningslagen” and as stipulated by RFR 2 Reporting for legal entities. Adoption of RFR
2 means that IBT applies all IFRS and statements as adopted by the EU to the extent possible
subject to the Annual Accounts Act, “Tryggandelagen” and considerations of the relation of
reporting and taxation. Preparation of financial reports in agreement with RFR 2 requires
application of some significant estimates regarding various evaluations and assessments of
principles of items for accounting purposes.
IBT has no transactions to report under total comprehensive income and a statement to that
effect is provided under the income statement.
The subsidiary, IBT Baby AB, was established in May 2017. During the second quarter of 2017
and third quarter of 2020, second quarter 2022, second quarter 2023 and second quarter 2024
IBT Baby AB received warrants at no cost from the parent company, which during the second
quarter have been sold to personnel employed by IBT at market price. Other transactions have
not occurred. As the company was established with a share capital amounting to 50 KSEK and
only incurred marginal establishment costs, consolidated income statement and balance sheet,
in all material aspects, equal those of the parent company and therefore no consolidation has
been made, supported by the Annual Accounts act, “Årsredovisningslagen 7 kap. 3a §”.
IFRS 16 'Leases'. The standard requires assets and liabilities related to all leases, with some
exceptions, to be recognized in the balance sheet. Early adoption is permitted. IBT only
prepares financial statements for legal entities and has thus chosen not to apply the rules in
IFRS 16. IBT instead applies paragraphs 2-12 of RFR 2 and thus lease payments continue to be
recognized as an expense on a straight-line basis over the lease term.
The changes that have entered into force and that apply from January 1, 2024 have not had any
significant impact on IBT's financial statements.
New accounting policies 2025 and later. As of January 1, 2027, IFRS 18 Presentation and
Disclosures in Financial Statements will become effective. The new standard will replace IAS 1
Presentation of Financial Statements. The purpose of IFRS 18 is to improve how companies
present their financial statements, focusing on the structure and classification of the income
statement and cash flow statement. The new standard also includes disclosure requirements
of management-defined performance measures and the nature of expenses, etc. IFRS 18 is
29!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
expected to have a material impact on most companies and it remains uncertain how this new
standard will be applicable under RFR 2.
No other new and amended accounting standards and interpretations that have been
published and come into force in 2025 and later are expected to have a material impact on the
Group's financial statements.
Functional currency and reporting currency
IBT´s functional currency is SEK. The financial statements are presented in SEK rounded to the
nearest thousand unless otherwise stated. Rounding to thousands may result in incorrect
amounts when summarized.
Recalculation from foreign currency
Transactions in foreign currencies are converted into the functional currency at the exchange
rates on the transaction date. Monetary assets and liabilities in foreign currencies are converted
into the functional currency at the exchange rates on the balance sheet date. Exchange rate
differences resulting from the conversion are reported in the financial items section in the
income statement. Non-monetary assets and liabilities are normally reported at historical cost
and converted to exchange rate at the date of transaction.
Financial instruments, IFRS 9
Financial instruments are reported at cost. Financial assets are deleted from the balance sheet
when the right to receive cash flows from the instrument has ceased or been transferred and
the Company has transferred in principle all risks and benefits associated with possession.
Financial liabilities are deleted from the balance sheet when the liability in the agreement has
been fulfilled or otherwise revoked.
Classification and valuation
Financial assets are classified based on the business model in which the asset is placed and
the cash flow character of the asset. If the financial asset is held within the framework of a
business model with the objective to collect contractual cash flows (hold to collect) and the
contractual terms relating to the financial asset at predetermined periods generates cash flows
solely comprised of capital and interest on the capital amount outstanding the asset will be
reported at accumulated cost.
If on the other hand the business model goal is met by both collecting contractual cash flows
and selling financial assets (hold to collect and sell), and the contractual terms of the financial
asset at determined periods generates cash flows solely comprised of payments of capital and
interest on the capital amount outstanding the asset will be reported at fair value under other
comprehensive income.
30!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
All other business models (other) where the purpose is speculation, carry for sale or where the
cash flow character eliminates other business models are consequently reported at fair value in
the income statement.
Financial assets are comprised of cash. Cash is comprised of immediately available cash held
by Swedish banks. The company applies the business model “hold to collect” regarding cash.
Financial liabilities are valued at fair value in the income statement provided they have a
determined price upon which IFRS 3 applies, carry for trade or if initially identified as liabilities
at fair value in the income statement. Other financial liabilities are valued at accumulated cost.
Depreciations
The company reports loss reserves for expected credit losses on financial assets valued at
accumulated cost. On each balance sheet date the company reports changes in expected credit
losses since initial reporting in the result.
The company values the credit losses for all financial assets amounting to 12 months expected
losses. For financial assets with significant increase in risk since the initial reporting a reserve is
reported based on credit losses over the entire duration of the asset (the general model).
The company reports expected credit losses for the remaining duration of all financial
instruments with significant increase in risk since the initial reporting, either estimated
individually or collectively, considering all reasonable and verifiable information, including
forward looking. The company evaluates expected credit losses from financial instruments in
such a manner that reflects objectively and by likelihood amounts ascertained by assessing an
interval of possible outcomes, discounted value of money and reasonable and verifiable
information regarding present conditions and forecasts regarding future economic conditions.
Cash is subject to the general model for depreciations. The exemption for limited credit risk on
the balance sheet date applies to cash.
The company defines default as if it is deemed unlikely that the counterparty will meet its
obligations due to indications of financial difficulty and passed due payments. Default is
regardless deemed to be the case when payment is 90 days past due. The company will delete
a receivable when no further possible cash flows are deemed to exist.
Accounts payable
Accounts payable are commitments to pay for goods or services acquired in operations from
suppliers. Amounts are unhedged and normally payable within 30 days. Accounts payable are
classified as current liabilities when due within one year or sooner (or a normal cycle of operation
if longer). If not, they are reported as long-term debt. Liabilities are initially disclosed at Fair value
and thereafter at accrued cost applying the effective interest method.
31!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Other liabilities
Expected duration for other liabilities is short, and therefore the liability is disclosed at nominal
amount without using the discounting method for accrued cost.
Accounts receivable and other receivables
Accounts receivable are reported at nominal value. Other receivables are reported at nominal
value. Fair value of accounts receivable and other receivables equals reported value as the
discounting effect is not material.
Non-current fixed assets
IBT´s development of internally generated non-current fixed assets are separated into a research
phase and a development phase. All costs related to the research phase are reported as costs
as they are incurred. All costs related to development are reported as assets according to IAS
38 if all the following criteria are met:
● the technical and commercial feasibility of the product or process has been
established so it may be used or sold
● the Company intends and is able to complete the intangible asset and either use it or
sell it
● there are prevailing conditions to use or sell the intangible asset
● It should be probable that the future economic benefits attributable to the asset will
flow to the Company
● There are necessary and adequate technical, financial and other resources to complete
the development and to use or sell the intangible asset.
● The expenditure attributable to the intangible asset during its development can be
reliably estimated.
Costs related to the project are charged to income in the development phase should the above
criteria not be met.
IBT’s assessment is that development of the production process for the pharmaceutical
candidate IBP-9414 meets the above criteria. Costs generated by the project have been
activated as of the point in time the criteria were met. The production process has been
assessed as completed for accounting purposes. Therefore, the intangible asset “production
process” is depreciated over its useful life of 20 years, with corresponds to the validity period
of existing and pending patent applications. Depreciation is reported in the R&D function in the
income statement.
The currently ongoing development project, IBP-9414, is not deemed to meet the above criteria
in IAS 38 to be activated as development in the balance sheet. The development costs are
therefore charged to income as incurred.
32!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Impairment of non-financial assets
Non-financial assets with uncertain periods of use or non-financial assets not ready for use, are
not depreciated but tested annually, or upon indication of impairment, for possible impairment.
Assets which are depreciated are evaluated regarding impairment any time events or changes
in circumstances indicate that the reported value may not be recovered. Write downs are made
by such amounts that reported value exceeds recoverable value. Recoverable value is the higher
of the assets Fair value reduced by sales costs and its useful value. Estimated impairment
requirements are grouped for assets at lowest possible levels where most significant
independent cash flow exists (cash generating groups). For assets (other than goodwill)
previously impaired a test is made at each balance sheet date if recovery should be made.
Liquid assets
Liquid assets in the balance sheet are cash and bank deposits.
Employee compensation
Employee compensation in the form of salaries, bonuses, paid vacation, paid sick leave, and
pension benefits are reported as earned. No pension commitments exist in the Company in
addition to pension premiums paid annually. All pension plans are fee based.
Cash flow statement
The cash flow is prepared according to the so-called indirect method.
Income
Income is reported at Fair value received or to be received. The company had no income as of
the balance sheet date.
Leasing
Payments made during the lease term are charged to the income statement on a straight-line
basis over the lease term.
Segment reporting
Operational segments are reported in a method consistent with internal reporting provided to
the highest executive decision maker. The Board of Directors are the Company’s highest
executive decision maker. The Company’s operations consist of only one branch of operation –
to develop pharmaceutical products. The Company’s report of total comprehensive income and
financial position is solely one operating segment.
33!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Taxes
The Company’s reported tax costs or tax income refers to current tax and changes in deferred
taxes. Current tax is calculated based on taxable income for the period in accordance with
prevailing tax laws. Current tax also includes adjustments from prior years.
IBT´s taxable losses amount to approximately 630 (494) MSEK. Deferred taxes are reported for
all temporary differences generated between the taxable value of assets and liabilities and their
reported values. Deferred tax receivables are reported to the extent that it is likely that future
taxable profits will be available, against which temporary differences may be offset. Deferred
tax receivables in the company’s financial statements will be activated only when it is certain
that taxable income will occur. No deferred tax receivable is reported in the company’s financial
statements.
Significant assessments and estimates
Assessments and estimates are appraised continuously and are based on historical experience
and other factors, including expectations of future events considered to be reasonable under
current circumstances. The Company makes assessments and estimates regarding the future.
The resulting estimates for accounting purposes will, by definition, seldom equal the actual
results. Assessments are also made regarding the Company’s accounting principles.
The currently ongoing development project, IBP-9414, is not deemed to meet the above criteria
in IAS 38 to be activated as development in the balance sheet. The development costs are
therefore charged to income as incurred.
Amounts are reported in KSEK (SEK in thousands). Amounts in parenthesis refer to the same
period in the previous year unless stated otherwise.
Note 2 Financial instruments
Fair value of other receivables, cash, accounts payable and other liabilities are estimated to
equal book value (accumulated cost) due to the short duration.
The effects on earnings are reported in the income statement against research and development
costs.
34!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 3 Leasing
IBT carries no financial leasing agreements. Leasing costs related to operational leasing are
charged at cost over the leasing period. No non-terminable leases exist after a duration of five
years.
Total future leasing costs regarding leasing agreements on the balance sheet date are as
follows:
Operational leasing
2024-12-31
2023-12-31
000's
Due for payment within one year
995
995
Due for payment within one and five years
825
694
Total
1,820
1,689
Operational leasing costs during the year
2024
2023
000's
Rent
780
739
Parking
55
66
Automobiles
216
263
Total
1,052
1,068
35!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 4 Personnel
Average number of employees
Average number of employees
2024
2023
Female
Male
Total
Female
Male
Total
Sweden
5
5
10
3
5
8
Total
5
5
10
3
5
8
Actual on
Dec, 31
2024
Actual on
31 Dec, 31
2023
Female
Male
Total
Female
Male
Total
Board of
Directors
3
2
5
3
2
5
Other
management
1
2
3
1
4*
5
Total
4
4
8
4
6
10
*One other management does not receive salary but invoices fees
Total salaries, pension- and social costs, 000's
2024
2023
Salaries and other compensation
16,679
12,654
Invoice fees other
management
0
2,190
Pensions
2,151
1,796
Social costs
4,339
33188
Other costs
369
403
Total
23,538
20,231
Variable compensation to management amounted to SEK 3,363 (1 653) k.
Board of Directors and committees
Fees are paid in accordance with the decision taken at the annual general meeting.
Chief Executive Officer
Base salary for the CEO, Mr. Staffan Strömberg, during 2024 amounted to SEK 3,355k plus SEK
1,678k in variable compensation.
36!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The CEO has fee based pension compensation and the company has therefore no other pension
commitments other than stated here. Pension premiums in 2024 amounted to SEK 1,024k.
The CEO and the company have a mutual notice period of six months. In addition, the company
has a commitment of severance pay equal to nine months salary upon termination by the
company.
Other management
Compensation to other management consists of base salary, performance compensation, other
compensation and pension premiums. Other management in the company refers to two persons
who along with the CEO comprise the executive management team.
The executive management team was in 2024 composed of CEO Mr. Staffan Strömberg, COO
Mr. Anders Kronström, and CFO, Mrs Maria Ekdahl.
Management compensation 2024
000's
Base
salaries/
fees
Variable
compensation
Other
benefits
Pension
costs
Total
Peter Rothschild, Chairman of the Board
747*
-
-
-
747
Margareta Hagman, Board member
188
-
-
-
188
Eva Idén, Board member
163
-
-
-
163
Anthon Jahreskog, Board member
218
-
-
-
218
Kristina Sjöblom Nygren, Board member
163
-
-
-
163
Staffan Strömberg, CEO
3,253
1,678
102
1,024
6,057
Other management (4)
2,874
1,686
79
559
5,199
Total
7,606
3,363
182
1,583
12,734
*Of which 400k as working Chairman
In order to serve IBT's long-term interests and ensure that senior executives have a market-
based and competitive remuneration package, the Board of Directors has decided to deviate
from the guidelines for executive remuneration with regard to variable remuneration for 2024.
The variable remuneration for senior executives for 2024 mainly consists of long-term share-
based remuneration
37!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The management group was in 2023 composed of CEO Mr. Staffan Strömberg, COO
Mr. Anders Kronström, CMO Mr. Jonas Rastad , CFO Mrs Maria Ekdahl and CCO Mr Robert
Molander.
Management compensation
2023
Base
salaries/fee
s
Performance
compensation
Other
benefits
Pension
costs
Total
000's
Peter Rothschild, Chairman of the
Board
727*
-
-
-
727
Margareta Hagman, Board
member
153
-
-
-
153
Eva Idén, Board member
153
-
-
-
153
Anthon Jahreskog, Board member
193
-
-
-
193
Kristina Sjöblom Nygren, Board
member
153
-
-
-
153
Staffan Strömberg, CEO
3 086
1 183
101
957
5 327
Other management (4)
6 132
470
18
498
7 118
Total
10 596
1 653
119
1 455
13 823
*Of which 400k as working Chairman
38!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 5 Breakdown of operating expenses by type of cost
000's
2024
2023
CRO, raw material and manufacturing
104,896
100,331
Personnel expenses
23,322
17,778
Depreciation and amortization
816
816
Other operating expenses
16,313
15,769
Totalt
145,347
134,694
Note 6 Audit fees
Deloitte AB, 000's
2024
2023
Auditing
270
263
Fees for audit-related consultancy services
16
65
Totalt
286
328
Auditing refers to compensation for review of the company’s internal controls, accounting,
annual report and administration by the Board of Directors and CEO.
Note 7 Intangible non-current assets
Activated development costs, 000's
2024
2023
Opening accumulated costs
16,225
16,225
Activated costs
-
-
Total cost
16,225
16,225
Opening accumulated depreciation
-6,523
-5,707
Depreciation
-816
-816
Total accumulated depreciation
-7,339
-6,523
Carrying amount at end of the period
8,886
9,702
Activated development costs refer to the production process of the pharmaceutical candidate
IBP-9414. Period of use is based on the underlying useful life of the patent of 20 years.
Depreciation is linear from 2016 and is reported in the R&D-function in the income statement
Impairment test
The criteria according to IAS 38 and IAS 36, respectively, require testing the immaterial fixed
assets for impairment whenever events or changed circumstances indicate that the reported
value may not be recovered.
39!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Activated costs referring to the production process have been assessed. The company has at
the time of disclosure of this financial report utilized the pharmaceutical candidate produced by
the production process in a clinical Phase II study in which 120 patients were dosed.
Technology transfer possibility of the manufacturing method has been verified by third parties.
The production process will be applied in the production of the drug upon potential market
approval.
Two independent companies, Apex Healthcare Consulting Ltd., and Clearview Healthcare
Partners have evaluated the market potential in 2014, 2016 and 2021 respectively, for IBP-9414
in the USA.
Their assessment of the market potential amounted to an interval of 200 MUSD to 360 MUSD
per annum.
The total assessment is that the criteria in IAS 38 are met.
Note 8
Shares in subsidiary
Name
Reg. No.
Domicile,
country
No.
Shares
Ownership
Book value
2024
Book value
2023
IBT Baby AB
559110-7353
Stockholm,
Sweden
50,000
100%
70,000
70,000
Total, SEK
70,000
70,000
IBT Baby AB manages incentive programs for key personnel employed by IBT AB.
IBT AB issues warrants which are sold by IBT Baby AB to employees of IBT AB eligible to
participate in the parent company’s incentive program as follows:
Share based incentive programs
WARRANTS 2022/2025
On May 4, 2022, the Annual General Meeting decided on an incentive program by designated
issue of warrants to the subsidiary IBT Baby AB. The maximum number of warrants to be
issued is 305,400.
In June 2022, 272,000 warrants were allotted at market terms at a price determined by
calculating the market price at the time of issue using the Black & Scholes method of
valuation.
The holder of warrants may during the period from June 1, 2025, through September 30, 2025,
for each warrant subscribe for 1.0061 new class B share in the company at a subscription
40!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
price per share amounting to SEK 128.77. On the balance sheet date, December 31, 2024, a
total of 272,000 warrants had been allotted. The remaining 32,500 warrants have not been
issued.
The warrants are subject to first right of refusal stipulating that the warrants shall be sold back
to IBT Baby AB should the employee, from the date of signing, terminate employment within
one year by 100%, within two years by 75 %, within three years by 50 %, and after three
years the holder may keep the warrants.
Based on the existing number of shares the dilution resulting from the adopted incentive
program, provided that all warrants are utilized for subscription of class B-shares, amounts to
approximately 1.98 percent of shares, and 1.53 percent of votes.
The warrants carry no dividend rights. The warrants are issued at market value and have thus,
have not resulted in any benefits which require accruals for social costs in the parent
company.
The subscription price per share exceeds the average market price of the IBT share during the
reporting period and therefore the options are not dilutive when calculating earnings per share.
The total market price for the 272,000 allotted warrants during the second quarter of 2022
amounts to KSEK 1,904, which is reported directly as shareholders equity in IBT.
Ownership of warrants
2022/2025
Number allotted
2024-12-31
Number issued
2024-12-31
Number allotted
2023-12-31
Number issued
2023-12-31
Staffan Strömberg, CEO
120,000
120,000
120,000
120,000
Anders Kronström, COO
75,000
75,000
75,000
75,000
Other
77,000
77,000
77,000
77,000
Total
272,000
272,000
272,000
272,000
WARRANTS 2023/2026
The Annual General Meeting on May 8, 2023 decided to introduce an incentive program,
Warrants 2023/2026 through a directed issue of warrants to the subsidiary IBT Baby AB. The
number of warrants amounts to a maximum of 165,000.
In May 2023, 155,000 warrants were allotted at market terms at a price determined by
calculating the market price at the time of issue using the Black & Scholes method of
valuation.
The holder of warrants may during the period from June 1, 2026 through September 30, 2026,
for each warrant subscribe for 1.0061 new class B-share in the company at a subscription
price per share amounting to SEK 100.05. On the balance sheet date, December 31, 2024 a
total of 155,000 warrants had been allotted. The remaining 10,000 warrants have not been
issued.
41!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The warrants are subject to first right of refusal stipulating that the warrants shall be sold back
to IBT Baby AB should the employee, from the date of signing, terminate employment within
one year by 100%, within two years by 75%, within three years the holder may keep the
warrants.
Based on the existing number of shares in the company, the dilution as a result of the
implemented incentive program, assuming that all warrants are exercised for new subscription
of B-shares, is approximately 1.14 percent of the shares and approximately 0.88 percent of
the votes.
The warrants carry no right to dividends. The warrants are issued at market value and have
thus, have not resulted in any benefits which require accruals for social costs in the parent
company.
The subscription price per share exceeds the average market price of the IBT share during the
reporting period and therefore the warrants are not dilutive when calculating earnings per
share.The total market price for 155,000 warrants issued during the second quarter of 2023
amounted to KSEK 510, which is reported directly as shareholders equity in IBT
Ownership of warrants
2023/2026
Number allotted
2024-12-31
Number issued
2024-12-31
Number allotted
2023-12-31
Number issued
2023-12-31
Staffan Strömberg, CEO
50,000
50,000
50,000
50,000
Anders Kronström, COO
25,000
25,000
25,000
25,000
Maria Ekdahl, CFO
25,000
25,000
25,000
25,000
Other
55,000
55,000
55,000
55,000
Total
155,000
155,000
155,000
155,000
WARRANTS 2024/2027
The Annual General Meeting on May 8, 2024 decided to introduce an incentive program,
Warrants 2024/2027 through a directed issue of warrants to the subsidiary IBT Baby AB. The
number of warrants amounts to a maximum of 165,000.
In May 2024, 165,000 warrants were allotted at market terms at a price determined by
calculating the market price at the time of issue using the Black & Scholes method of
valuation.
The holder of warrants may during the period from June 1, 2027 through September 30, 2027,
for each warrant subscribe for 1 new class B-share in the company at a subscription price per
share amounting to SEK 176.83. On the balance sheet date, December 31, 2024 a total of
165,000 warrants had been allotted.
The warrants are subject to first right of refusal stipulating that the warrants shall be sold back
to IBT Baby AB should the employee, from the date of signing, terminate employment within
42!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
one year by 100%, within two years by 75%, within three years the holder may keep the
warrants.
Based on the existing number of shares in the company, the dilution as a result of the
implemented incentive program, assuming that all warrants are exercised for new subscription
of B-shares, is approximately 1.21 percent of the shares and approximately 0.93 percent of
the votes.
The warrants carry no right to dividends. The warrants are issued at market value and have
thus, have not resulted in any benefits which require accruals for social costs in the parent
company.
The subscription price per share exceeds the average market price of the IBT share during the
reporting period and therefore the warrants are not dilutive when calculating earnings per
share. The total market price for 165,000 warrants issued during the second quarter of 2024
amounted to KSEK 2,013, which is reported directly as shareholders equity in IBT
Ownership of warrants
2024/2027
Number allotted
2024-12-31
Number issued
2024-12-31
Number allotted
2023-12-31
Number issued
2023-12-31
Staffan Strömberg, CEO
50,000
50,000
Anders Kronström, COO
25,000
25,000
Maria Ekdahl, CFO
25,000
25,000
Other
65,000
65,000
Total
165,000
165,000
Total number of allotted warrants in existing incentive programs
Allotted
warrants, year
Issued
warrants
Strike
price*
Value per
allotted
warrant
Volatility,
%*
Risk-free
interest, %
Value
per
share
Expiry,
year
2022 (2022/2025)
272,000
128.77
7
39
1.32
66.90
2025
2023 (2023/2026)
155,000
100.05
3.29
39
2.76
43.40
2026
2024 (2024/2027)
165,000
176.83
12.20
40
2.55
96.00
2027
Total
592,000
-
-
-
-
-
-
*Expected future volatility is ascertained by comparison of historical average and median values for
comparable listed companies in the same sector as IBT based on analysis in S&P Capital IQ.
Note 9 Other receivables
000's
2024
2023
Taxes
3,474
2,101
Other receivables
523
865
Total cost
3,997
2,966
43!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 10 Prepaid expenses and accrued income
000's
2024
2023
Accrued interest income
769
3,771
Prepaid rent
231
195
Prepaid insurance
330
293
Prepaid manufacturing costs
1,550
5,229
Other prepaid expenses
344
45
Total cost
3,224
9,533
The maximum credit risk exposure on the balance sheet date equals reported value.
Note 11 Cash and bank deposits
000's
2024
2023
Bank deposits
223,388
329,064
Total cost
223,388
329,064
The Company’s liquidity consists solely of cash deposits. Total liquidity on the balance sheet
date December 31, 2024, amounted to MSEK 223.4 (329.1) of which USD amounted to MSEK
97.2 (112.8) and EUR amounted to MSEK 56.7 (25.8).
Note 12 Accrued expenses and prepaid income
000's
2024
2023
R&D costs
15,652
11,820
Social costs and special salary taxes
1,428
1,402
Vacation pay
2,161
1,689
Board fees
95
83
Consultancy cost
1,552
-
Other accrued expenses
1,002
340
Total
21,890
15,334
All accrued expenses are due for payment within twelve months.
Note 13 Significant events after the reporting period
No significant events have occurred after the reporting period.
44!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 14 Board of Directors recommendation of appropriation of profits
SEK
2024
Recommendation of appropriation of profits or loss
The Board of directors propose that the following surplus:
Income carried forward
-465,346,337
Surplus reserve
768,841,897
Result for the period
-136,904,518
Total
166,591,042
Be appropriated as follows:
Income carried forward
166,591,042
Total
166,591,042
Note 15 Related party transactions
Compensations to the Board of directors are paid in accordance with the annual general
meeting.
The Chairman of the Board, Mr. Peter Rothschild, receives Board fees amounting to KSEK 326
per annum, KSEK 400 annually as operational Chairman, and KSEK 21 for the work in the
Remuneration Committee.
Bonus was paid during the first quarter to Anders Kronström amounting to KSEK 267.
Bonuses were paid during the second quarter to Staffan Strömberg amounting to KSEK 1,419
and to Anders Kronström KSEK 709, and to Maria Ekdahl amounting to KSEK 709.
Bonus was paid during the fourth quarter to Staffan Strömberg amounting to KSEK 259 as
variable bonus.
Eva Idén, through her company Better & Beyond, has invoiced KSEK 52 for consulting
services within CMC
KSEK 2,013 cash has been transferred from IBT Baby to IBT AB.
No other significant related party transactions have occurred.
Note 16 Pledged assets and contingent liabilities
2024
2023
Pledged assets and contingent liabilities
None
None
45!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Note 17 Result per share
Calculations are in accordance with IAS 33 Earnings per share. Earnings per share are
calculated by dividing the result for the period with the weighted average number of outstanding
shares during the period.
Result per share, SEK
2024
2023
Result for the period, 000's
-136,905
-123,068
Weighted average number of shares before and after dilution*
13,471,420
12,364,614
Result per share before and after dilution
-10.16
-9.95
Note 18 Share capital development (SEK)
Period
Transaction
Change
Series A
shares
Series B
shares
Share
capital
Quota
value
Subscription
price
Total
Invested
2011-11-22
Founding
50,000
50,000
1.00
1.00
50,000
2015-09-15
Share issue
40,000
90,000
1.00
1,320,00
52,800,000
2015-09-15
Bonus issue
90,000
500,000
5.56
-
52,850,000
2016-02-12
Split/reclass
-90,000
74,066
1,760,480
500,000
0.27
-
52,850,000
2016-05-30
Share issue
-
148,132
3,520,960
1,500,000
0.27
27.30
153,016,212
2017-11-30
Share issue
-
-
1,100,000
1,799,802
0.27
95.00
257,516,212
2018-02-05
Share issue
-
155,538
4,435,663
3,051,120
0.27
95.00
693,680,307
2018-02-13
Share issue
-
-
31,345
3,059,663
0.27
95.00
696,658,082
2023-07-04
Share issue
-
75,547
2,169,689
3,671,595
0.28
45.00
797,693,702
Totalt
0
453,283
13,018,137
3,671,595
0.28
-
797,693,702
Note 19 Financial risk management
General
The financial risks related to the Company’s operations are mainly liquidity, currency, and
counterparty risks.
Liquidity risks
Liquidity risks are such risks as not having access to liquidity to meet the Company’s operational
requirements. The Company has no financial liabilities with agreed duration. Other liabilities are
commitments to pay for goods or services obtained during operations from suppliers. The
46!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
amounts are unhedged and normally payable within 30 days. Capital needs are monitored by
budget review.
Financing strategy
The Company’s capital requirements have previously been met by capital injections from its
former parent company, BioGaia and share issue in connection with listing the Company on
Nasdaq First North in March 2016. To date, IBT has received 82 MSEK from BioGaia and 100
MSEK from other shareholders in connection with the May 2016 share issue.
During November 2017 IBT generated MSEK 104.5 in a directed share issue to institutional
investors and in January 2018, a preferred share issue generated MSEK 439.1. Total capital
generated amounting to approximately MSEK 543.6 prior to transaction costs and
approximately MSEK 528 post transaction.
In July 2023, IBT raised approximately MSEK101 before issue costs and approximately SEK 96
million after issue costs in a rights issue. This capital will be used to begin preparations for
commercial launch.
As the Company’s pharmaceutical candidate IBP-9414 reaches important milestones in its
pharmaceutical development, additional financing possibilities are available. As a listed
company in Sweden the Company can issue new shares with preemptive rights for its
shareholders. Other possible financing methods are licensing specific rights to the
pharmaceutical to pharmaceutical company and a share issue to new investors, conditional
upon being possible on terms acceptable to current shareholders.
Obtaining loans for financing is not deemed suitable other than as a temporary solution before
the Company reaches profitability and has positive cash flow. The company has only financial
liabilities with short duration which are due for payment within 12 months.
Access to capital may be limited at times when needed by the Company.
Credit risks
Only investments in instruments with low credit risk and high liquidity are allowed. The company
works with established and creditworthy counterparties and continuously evaluates receivables
to ensure a low exposure to bad debts. To reduce this risk, IBT places its excess liquidity in
accounts in Swedish banks. On the balance sheet date, the company had approximately MSEK
38 invested 6 month fixed rate accounts and MSEK 64 invested in 3 month fixed rate accounts.
Currency risks
Currency risk is the risk that the value of assets and liabilities will vary due to changes in
exchange rates. The majority of IBT's development costs consist of commitments in other
currencies. If the SEK decreases in value against the currency in question, it can have a
significant impact on the company's position and results. The currencies to which IBT has the
47!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
greatest exposure are USD and EUR. So far, IBT has offset cost increases by buying USD and
EUR in the past when the exchange rate was more favorable. On the balance sheet date, foreign
cash and cash equivalents would have been affected by a 10% change in the exchange rate by
SEK 15.4 million.
FINANCIAL DEFINITIONS
Key ratios
Definition
Motive
Average number
of shares
Average number of shares during the
year
Relevant in calculating income and
cash flow per share
Net sales
Sales for the year
Sales of services
Reporting period
January 1 - December 31, 2024
Defines time period comprised by
this financial report
Result per share
Result for the year divided by average
number of shares
Result allocated per share
Cash flow per
share*
Cash flow for the year divided by
average number of shares
Measure to describe cash flow
allocated to one share during the
year
Number of
shares*
Number of shares at the end of the
year
Relevant for calculating
shareholders’ equity allocated to
one share
Shareholders
equity/share*
Total shareholders’ equity divided by
the number of shares at the end of the
year
Measure to describe shareholder’s
equity per share
Equity ratio*
Total shareholders’ equity as a
percentage of total assets
Measure to evaluate the company’s
ability to meet its financial
obligations
*The Company presents certain financial measures in the Year-end report not defined by IFRS. The
Company deems that these measures provide valuable additional information for investors and
management of the Company as they enable evaluation and benchmarking of the Company’s
performance. As all companies do not calculate financial measures the same way, these measures are
not always comparable to those used by other companies. These financial measures shall therefore not
be viewed as replacements for those defined by IFRS. The financial definitions are not defined by IFRS
unless otherwise stated. See deduction of certain key figures.
48!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
BOARD’S ASSURANCE
The Board of Directors and CEO hereby certify that this report gives a true and fair
presentation of the Company’s operations, financial position and result of operations, and
describes material risks and uncertainties facing the Company.
The Annual Report was approved for issuance by the Board of Directors on March 26, 2025
and will be subject to approval at the annual general meeting on May 8, 2025.
Stockholm, March 26, 2025
Peter Rothschild
Chairman
Eva Idén
Director
Margareta Hagman
Director
Kristina Sjöblom Nygren
Director
Anthon Jahreskog
Director
Staffan Strömberg
CEO
NB: This is a translation of the Swedish annual report. If any discrepancies exist, the Swedish
version shall prevail.
Our Auditor’s Report was submitted on March 26, 2025
Deloitte AB
Jenny Holmgren
Authorized public accountant
49!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Auditor’s report
To the general meeting of the shareholders of Infant Bacterial Therapeutics AB (publ)
corporate identity number 556873-8586
Report on the annual accounts
Opinions
We have audited the annual accounts of Infant Bacterial Therapeutics AB (publ) for the
financial year 2024-01-01 - 2024-12-31. The annual accounts of the company are included on
pages 16-48 in this document.
In our opinion, the annual accounts have been prepared in accordance with the Annual
Accounts Act and present fairly, in all material respects, the financial position of Infant
Bacterial Therapeutics AB (publ) as of 31 December 2024 and its financial performance and
cash flow for the year then ended in accordance with the Annual Accounts Act. The statutory
administration report is consistent with the other parts of the annual accounts.
We therefore recommend that the general meeting of shareholders adopts the income
statement and balance sheet.
Basis for Opinions
We conducted our audit in accordance with International Standards on Auditing (ISA) and
generally accepted auditing standards in Sweden. Our responsibilities under those standards
are further described in the Auditor’s Responsibilities section. We are independent of Infant
Bacterial Therapeutics AB (publ) in accordance with professional ethics for accountants in
Sweden and have otherwise fulfilled our ethical responsibilities in accordance with these
requirements.
We believe that the audit evidence we have obtained is sufficient and appropriate to provide a
basis for our opinions.
Key Audit Matters
Key audit matters of the audit are those matters that, in our professional judgment, were of
most significance in our audit of the annual accounts of the current period. These matters
were addressed in the context of our audit of, and in forming our opinion thereon, the annual
accounts and as a whole, but we do not provide a separate opinion on these matters.
Research and development costs
The company’s costs for research and development as of December 31, 2024 amount to
TSEK 126 051 after exchange rate gains on foreign currency forward contracts and currency
deposits and is a significant amount in the income statement. It is management’s assessment
that the entire amount should be expensed instead of being capitalized as intangible assets
since the criteria in IAS 38 regarding capitalization are not deemed to be fulfilled. The
50!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
company describes its positions in the accounting principles on page 28. Our audit
procedures included, but were not limited to:
•
Examination of a number of transactions to ensure correct classification
•
Examination of the company’s analysis and assumptions that form the basis of the
company's position for the question
•
Examination that the required disclosures are provided in the annual accounts
Other information than the annual accounts
This document also contains other information than the annual accounts and consolidated
accounts on pages 1-15 and 65-66. The other information also consists of the Remuneration
Report that we obtained prior to the date of this audit report. The Board of Directors and the
Managing Director are responsible for this other information.
Our opinion on the annual accounts does not cover this other information and we do not
express any form of assurance conclusion regarding this other information.
In connection with our audit of the annual accounts and, our responsibility is to read the
information identified above and consider whether the information is materially inconsistent
with the annual accounts. In this procedure we also take into account our knowledge
otherwise obtained in the audit and assess whether the information otherwise appears to be
materially misstated.
If we, based on the work performed concerning this information, conclude that there is a
material misstatement of this other information, we are required to report that fact. We have
nothing to report in this regard.
Responsibilities of the Board of Directors and the Managing Director
The Board of Directors and the Managing Director are responsible for the preparation of the
annual accounts and that they give a fair presentation in accordance with the Annual Accounts
Act. The Board of Directors and the Managing Director are also responsible for such internal
control as they determine is necessary to enable the preparation of annual accounts that are
free from material misstatement, whether due to fraud or error.
In preparing the annual accounts, The Board of Directors and the Managing Director are
responsible for the assessment of the company’s ability to continue as a going concern. They
disclose, as applicable, matters related to going concern and using the going concern basis of
accounting. The going concern basis of accounting is however not applied if the Board of
Directors and the Managing Director intends to liquidate the company, to cease operations, or
has no realistic alternative but to do so.
Auditor’s responsibility
Our objectives are to obtain reasonable assurance about whether the annual accounts as a
whole are free from material misstatement, whether due to fraud or error, and to issue an
auditor’s report that includes our opinions. Reasonable assurance is a high level of assurance,
but is not a guarantee that an audit conducted in accordance with ISAs and generally
51!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
accepted auditing standards in Sweden will always detect a material misstatement when it
exists. Misstatements can arise from fraud or error and are considered material if, individually
or in the aggregate, they could reasonably be expected to influence the economic decisions of
users taken on the basis of these annual accounts.
A further description of our responsibilities for the audit of the management’s administration is
located at the Swedish Inspectorate of Auditors website:
www.revisorsinspektionen.se/revisornsansvar
http://www.revisorsinspektionen.se/ri/showdocument/documents/ This description forms part
of the auditor´s report.
Opinions
In addition to our audit of the annual accounts, we have also audited the administration of the
Board of Directors and the Managing Director of Infant Bacterial Therapeutics AB (publ) for the
financial year 2024-01-01 - 2024-12-31 and the proposed appropriations of the company’s
profit or loss.
We recommend to the general meeting of shareholders that the profit to be appropriated in
accordance with the proposal in the statutory administration report and that the members of
the Board of Directors and the Managing Director be discharged from liability for the financial
year.
Basis for Opinions
We conducted the audit in accordance with generally accepted auditing standards in Sweden.
Our responsibilities under those standards are further described in the Auditor’s
Responsibilities section. We are independent of Infant Bacterial Therapeutics AB (publ) in
accordance with professional ethics for accountants in Sweden and have otherwise fulfilled
our ethical responsibilities in accordance with these requirements.
We believe that the audit evidence we have obtained is sufficient and appropriate to provide a
basis for our opinions.
Responsibilities of the Board of Directors and the Managing Director
The Board of Directors is responsible for the proposal for appropriations of the company’s
profit or loss. At the proposal of a dividend, this includes an assessment of whether the
dividend is justifiable considering the requirements which the company's type of operations,
size and risks place on the size of the company's equity, consolidation requirements, liquidity
and position in general.
The Board of Directors is responsible for the company’s organization and the administration of
the company’s affairs. This includes among other things continuous assessment of the
company’s financial situation and ensuring that the company's organization is designed so
that the accounting, management of assets and the company’s financial affairs otherwise are
controlled in a reassuring manner. The Managing Director shall manage the ongoing
administration according to the Board of Directors’ guidelines and instructions and among
other matters take measures that are necessary to fulfill the company’s accounting in
52!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
accordance with law and handle the management of assets in a reassuring manner.
Auditor’s responsibility
Our objective concerning the audit of the administration, and thereby our opinion about
discharge from liability, is to obtain audit evidence to assess with a reasonable degree of
assurance whether any member of the Board of Directors or the Managing Director in any
material respect:
• has undertaken any action or been guilty of any omission which can give rise to liability to
the company, or
• in any other way has acted in contravention of the Companies Act, the Annual Accounts
Act or the Articles of Association.
Our objective concerning the audit of the proposed appropriations of the company’s profit or
loss, and thereby our opinion about this, is to assess with reasonable degree of assurance
whether the proposal is in accordance with the Companies Act.
A further description of our responsibilities for the audit of the management’s administration is
located at the Swedish Inspectorate of Auditors website:
www.revisorsinspektionen.se/revisornsansvar
http://www.revisorsinspektionen.se/ri/showdocument/documents/ This description forms part
of the auditor´s report.
Stockholm 26 March 2025
Deloitte AB
Signature on Swedish original
Jenny Holmgren
Authorized Public Accountant
53!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
CORPORATE GOVERNANCE REPORT IBT
IBT is a Swedish limited company whose B-shares are listed on Nasdaq Stockholm. The
company is governed by the AGM, the Board of Directors, the President and the executive
management in accordance with the Companies Act, the Articles of Association, rules of
procedure for the Board and the CEO's instructions and the Swedish Code of Corporate
Governance. The Board is responsible for evaluating established goals and continuously
evaluating IBT's financial position and earnings and evaluating the operational management.
The share capital consists of 453,283 Class A shares with 10 voting rights per share and
13,018,137 Class B-shares with one voting right per share.
Compliance with the Swedish Code of Corporate Governance (Svensk Kod för
Bolagsstyrning), common stock market code and applicable stock market rules
The purpose of the Code is to strengthen confidence in Swedish listed companies by promoting
a positive development of the company's corporate governance. The code is based on the
principle of "comply or explain" which means that a company can make deviations from the
code but these must then be explained.
IBT has not deviated from any of the rules specified in the Code.
IBT has not been subject to a decision by Nasdaq Stockholm's disciplinary committee or a
statement by the Swedish Securities Council (Arbetsmarknadsnämnden).
Environment and responsibility
IBT's operations do not pose any specific environmental risks and do not require any specific
environmental permits or decisions from authorities. The Board of Directors believes that the
company conducts its operations in accordance with applicable health and safety rules and
offers its employees a safe and healthy working environment.
Diversity and gender equality
IBT should be a workplace where diversity and gender equality are natural parts of the business.
A workplace characterized by diversity and gender equality is necessary for IBT to be an
attractive workplace and to achieve set goals. Recruitment shall be based on competence
requirements, diversity and gender equality.
Sustainability
IBT is to be perceived as an innovative and creative company, which stands for quality and
health and plays a role in society. It is important for IBT to work with sustainability. Respect for
human rights, the environment and anti-corruption must characterize our everyday lives through
business strategies, financing processes, investments and purchases.
54!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
According to the Swedish Annual Accounts Act (Årsredovisningslagen), there is no requirement
that the Company prepare a Sustainability Report.
Articles of Association
In accordance with IBT's articles of association, the Company will develop, manufacture, market
and sell pharmaceuticals directly or through subsidiaries or other forms of part-ownership or
partnerships and conduct related operations. The seat of the Board is Stockholm.
The Articles of Association do not contain any provisions on the appointment or dismissal of
directors or the amendment of the Articles of Association. Nor do the Articles of Association
contain any restrictions on the number of votes each shareholder can cast at a general meeting.
The Articles of Association can be found on IBT's website under the heading Investors /
Corporate Governance.
Annual General Meeting
In accordance with the Swedish Companies Act, the Annual General Meeting is IBT's highest
decision-making body and at the Annual General Meeting the shareholders exercise their voting
rights on key issues, for example establishing a report on comprehensive income and financial
position, disposition of IBT's results, granting discharge from the Board of Directors and the
Board of Directors, election of the Board of Directors and the CEO and remuneration to the
Board of Directors and auditors. In addition to the AGM, an Extraordinary General Meeting can
be called. In accordance with the Articles of Association, notice of the Annual General Meeting
and Extraordinary General Meeting are published in Post- och Inrikes Tidningar and on IBT's
website.
Annwall & Rothschild Investment AB, owns 8.72 percent of the capital and 29.94 percent of the
votes in the company.
Annual General Meeting 2024
At IBT's Annual General Meeting on May 8, 2024, The Annual General Meeting decided, inter
alia, the following:
● Approval of the income statement and balance sheet
● Granted discharge from liability for Board members and the CEO
● That no dividend is paid
● That the board shall consist of five members without deputies
● Re-election of board members Margareta Hagman, Eva Idén, Anthon Jahreskog,
Kristina Sjöblom Nygren, Peter Rothschild
● Re-election of Peter Rothschild as Chairman
● Re-election of the registered accounting firm Deloitte AB
● That remuneration to be paid to the Chairman of the Board of SEK 340,000 and an
additional remuneration for the work of Chairman of the Board of SEK 400,000 and
to other members not employed by the company by SEK 170,000 each. In addition,
remuneration shall be paid to members of the Remuneration Committee in the
amount of SEK 44 000 to the Chairman and SEK 22 000 to each of the other
55!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
members of the committee. And that fees shall be paid to members of the newly
established Audit Committee with SEK 50,000 to the Chairman and SEK 25,000 to
each of the other members of the Committee
● That audit fees should be paid according to approved invoice
● Approval of nomination committee in accordance with the nomination committee's
proposal
● Approval of the Board’s remuneration report
● Amending the articles of association, and on authorization for the Board to decide
on issue of class B-shares in accordance with the Board’s proposal
● The introduction of a new incentive program
The Annual General Meeting 2025
The 2025 Annual General Meeting will be held on May 8, 2025 in Stockholm.
Notice of Annual General Meeting
Notice of Annual General Meeting shall be made through advertising in Post- och Inrikes
Tidningar and on the company's website. That notice should be announced in Svenska
Dagbladet and on the company's website.
Nomination Committee
The 2024 AGM decided that a nomination committee should be appointed as follows:
“The Chairman of the Board of Directors shall convene the three largest shareholders in
the company in terms of voting rights, who shall each appoint one member who, together
with the Chairman of the Board of Directors, shall constitute the Nomination Committee. In
the composition of the Nomination Committee, the ownership structure as of June 30,
2024 shall determine which are the largest shareholders in terms of votes. The member
appointed by the largest shareholder in terms of voting rights in the nomination committee
at that time shall be the chairman of the nomination committee. If any of the three largest
shareholders waives its right to appoint a member of the nomination committee, the next
largest shareholder shall be given the opportunity to appoint a member of the nomination
committee. The names of the three members shall be announced as soon as they are
appointed, but no later than six months before the 2025 Annual General Meeting. The
Nomination Committee's term of office extends until a new Nomination Committee is
appointed.”
56!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
If the shareholder by whom the member was appointed is no longer one of the three
largest shareholders in terms of votes, such member may, if the Nomination Committee
deems it appropriate, be dismissed and a member for the next largest shareholder in
terms of votes be given the opportunity to take his/her place. If an appointed member of
the nomination committee resigns from the nomination committee for any other reason,
the shareholder who appointed the member in question shall be entitled to appoint a new
member of the nomination committee. If the shareholder declines to appoint a new
member, the Nomination Committee shall, if it considers it appropriate in view of the
remaining term of office, ask the next largest shareholder in terms of voting rights whether
it wishes to appoint a member of the Nomination Committee.
The Nomination Committee shall prepare proposals on the following matters to be
submitted to the 2025 Annual General Meeting for resolution:
a) proposal for the chairman of the meeting
b) proposal for the Board of Directors
c) proposal for Chairman of the Board
d) proposal for the remuneration of the Board of Directors
e) proposal for auditor
f) proposal for auditor fees
g) proposals regarding the Nomination Committee for the 2026 Annual General Meeting.
Mandate
The 2024 AGM decided to authorize the Board of Directors to decide, on one or more
occasions during the period until the next AGM, on the issue of shares. The Board of
Directors shall be able to decide on the issue of shares with deviation from the
shareholders' preferential rights. A new issue may be made with or without a provision for
non-cash payment, set-off or other conditions as referred to in Chapter 13, Section 5, first
paragraph 6 of the Swedish Companies Act.
In the case of issues of shares made with deviation from the shareholders' preferential
rights (directed issues), the Board of Directors shall not be able to make a decision that
entails that the share capital is increased by more than twenty percent in relation to the
share capital that exists when the issue authorization is first used for a directed issue.
Issues under the authorization shall be made on market terms. The Board of Directors shall
have the right to determine the other terms and conditions for issues under this
authorization and who shall be entitled to subscribe for the shares. The purpose of the
authorization is to give the Board of Directors flexibility in its work to ensure that the
company can be appropriately provided with capital for the financing of the company's
continued clinical operations and to enable a broadening of the ownership base in the
company.
57!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The Board
According to IBT's Articles of Association, the Board of Directors shall consist of a minimum
of three and a maximum of ten members and no deputies. The Board is elected annually at
the AGM for the period until the end of the next AGM. Since the 2023 AGM, the Board has
consisted of five members elected by the AGM with no deputies. Peter Rothschild is an
indirect shareholder in IBT through Annwall & Rothschild Investment AB. The other members
are independent in relation to the company and its management.
The Chief Executive Officer is not a member of the Board but is co-opted to all Board
meetings. Other employees of the company participate in Board meetings in the capacity of
presenters. The Board has adopted rules of procedure that include the division of work
between the Board and the CEO and the structure of the Board's work during the year. In
addition to the responsibilities that generally apply under the Swedish Companies Act and the
Articles of Association, the Board's rules of procedure regulate the following:
- Hold at least 4 board meetings, in addition to the statutory meeting
- Determine the overall objectives of the company's operations and decide on the
company's strategy and evaluate the operational management and risk assessment in
the company.
- Approve budget and corresponding long-term plans including investment budget
- Process matters relating to investments and the like in the amount of five million
(5,000,000) SEK or other commitments for the company, which entails a cost to the
company exceeding five million (5,000,000) SEK
- Decide on the purchase and sale of real estate, shares or acquisitions of another
company's operations in excess of five hundred thousand (500,000 SEK)
- Determine the annual report, the directors' report and the interim reports
- Borrowing
- Enter into an agreement with a term of more than three years
- Initial processes of large scope and settlement of disputes of significant importance
- Other issues of significant economic or other importance
The Board of Directors is responsible for monitoring the Company's financial position, for
monitoring the efficiency of the Company's internal control, internal audit and risk management,
being informed of the audit of the 2024 financial statements and for reviewing and monitoring
the auditor's impartiality and independence.
In addition, the Board of Directors has adopted the CEO's instruction, certificate instruction
including instructions regarding liquidity management and currency management policy. The
work order, CEO instruction and attestation instruction are tested at least once a year.
58!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The Board of Directors presence in 2024
Independent in relation to
Name
Position
Member
since
Company and
senior
management
Major
shareholders
Attendance
2024
Peter Rothschild
Chairman of the
Board
4
2011
No
1
No
2
9/9
Margareta
Hagman
Board member
3
2015
Yes
Yes
9/9
Eva Idén
Board member
2017
Yes
Yes
9/9
Anthon Jahreskog
Board member
3,4
2017
Yes
No
9/9
Kristina Sjöblom
Nygren
Board member
2018
Yes
Yes
9/9
1
In his role as working Chairman, Peter Rothschild is not considered independent in relation to the
company.
2
Peter Rothschild is a partner in Annwall & Rothschild Investments AB, the Company's largest
shareholder.
3
Member in Audit Committee. The Remuneration Committee had two meetings during 2024 with full
attendance.
3
Member in Remuneration Committee. The Remuneration Committee has, besides ongoing contact, had
two meetings during 2024 with full attendance.
If a member has not been able to attend a board meeting, this member has had the opportunity
to present his / her views to the Chairman before the meeting.
Board meeting agenda is as follows where appropriate:
- Business Plans
- Business follow-up
- Investments
- Strategy
- Performance reports
- Significant agreement
- Budget
- Financial statements
The Board continuously evaluates its work through open discussions and annually performs a
written evaluation of its work. The Nomination Committee is informed of the results of the
evaluation.
59!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Remuneration to the Board
The 2024 Annual General Meeting decided on a Board fee of SEK 340,000 for the
Chairman and an additional fee for work as Executive Chairman of SEK 400,000 and SEK
170,000 for the other members, as well as fees for committee work. Remuneration to
members of the Remuneration Committee of SEK 44,000 to the Chairman and SEK 22,000
to each of the other members of the Remuneration Committee. Fees shall also be paid to
members of the Audit Committee in the amount of SEK 50,000 to the Chairman and SEK
25,000 to each of the other members of the Audit Committee.
Chairman of the Board
The Chairman of the Board is responsible for leading the work of the Board and for the Board
to fulfill its obligations in accordance with the Companies Act and the Board's rules of
procedure. Through continuous contacts with the CEO, the Chairman of the Board shall monitor
the company's development and ensure that the Board receives the information required for the
Board to fulfill its commitment. In addition, the Chairman, as a working Chairman of the Board,
actively participates in financing issues, licensing issues and presentations to the market and
assists company management in business development. Peter Rothschild has been Chairman
of the Board since 2011.
The CEO
The CEO is responsible for the company's business development and manages and coordinates
day-to-day operations. The CEO has an instruction decided by the Board of Directors, which
regulates, among other things, his work with management and development of the company as
well as continuous reporting and decision-making to the Board. The CEO prepares the
necessary information and decision-making documentation such as reports regarding, among
other things, the company's finances, order situation, significant business and strategic issues
before Board meetings, and is a rapporteur and submits motivated proposals for decisions. In
addition, the President keeps the Chairman of the Board regularly informed about the
company's operations.
The Managing Director is solely responsible for external communication.
The Board annually evaluates the CEO's work. In this evaluation, no one from the company
management is present.
Management
The management of IBT consists of three people.
The management team is led by the CEO and is responsible for planning, directing and
monitoring the day-to-day operations. Minuted meetings are held every week. The powers and
responsibilities of the CEO, in addition to being regulated by the Companies Act, are defined in
the CEO instructions adopted by the Board. The powers and responsibilities of company
management are defined in job descriptions and attestation instructions.
60!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Remuneration Committee
The Board has appointed a Remuneration Committee consisting of Chairman of the Board Peter
Rothschild and Board member Anthon Jahreskog. Anthon Jahreskog is Chairman of the
Remuneration Committee.
The Remuneration Committee shall prepare questions regarding remuneration and other terms
of employment for the CEO and other senior executives who together form the company
management. The Remuneration Committee has held two meetings during 2024. Peter
Rothschild and Anthon Jahreskog were present at all three meetings.
Principles for remuneration to senior executives are set at the Annual General Meeting. The
remuneration committee's task is to prepare proposals for senior executives in accordance with
these principles.
Audit Committee
The Board of Directors has appointed an Audit Committee consisting of Board member
Margareta Hagman and Board member Anthon Jahreskog. Ms. Hagman is the Chair of the
Audit Committee.
The Audit Committee is responsible for preparing matters relating to risk assessment, internal
control, financial reporting and auditing. As well as other issues that the Board chooses to let
the Audit Committee investigate and prepare. The Audit Committee held two meetings in
2024, with Margareta Hagman and Anthon Jahreskog attending each.
Auditors
IBT's auditors are normally elected for a period of one year at the AGM. At the 2024 Annual
General Meeting, re-election of Deloitte AB was resolved for the period up to the end of the
Annual General Meeting that will be held in 2025. The Auditing Company has appointed Jenny
Holmgren as the designated Auditor. Remuneration to the auditors is paid, in accordance with
the decision of the Meeting, on an ongoing basis.
The auditors review the Board of Directors and the CEO's management of the company and the
quality of the company's financial reporting. The auditors also carry out, on behalf of the Board,
an audit of the financial statements, an audit of the annual report, and a review of a quarterly
report.
The auditor’s report their audit to the shareholders through the audit report, which is presented
at the AGM. In addition, written and oral reports are submitted to the company management
and the board. At the board meeting in connection with the review of the third quarter, the
auditor participates in the reporting of comments from the ongoing review during the financial
year regarding the company's internal control and preparation for the annual accounts.
61!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The auditors also submit an audit opinion on the corporate governance report and a report on
the review of remuneration to senior executives.
For information on remuneration to the auditors, see note 6 in the annual report.
The Board of Directors has decided that independent members of the Board possess
accounting expertise as well as the Board's ongoing review of the financial reporting and with
regard to the company's limited size and scope of transactions, not to appoint an Audit
Committee. Furthermore, the entire Board meets with the auditor at least once a year without
the presence of the company's CEO or another of the company management.
The Board's description of internal control regarding the financial reporting
for the financial year 2024.
Introduction
According to the Swedish Companies Act, the Swedish Annual Accounts Act and the Swedish
Code of Corporate Governance, the Board is responsible for internal control. This description
has been prepared in accordance with these provisions and thus limited to internal control over
the financial reporting.
Internal control over financial reporting
The Board of Directors is responsible for ensuring that the company's organization is designed
so that the accounting, asset management and the company's financial conditions are
otherwise controlled in a satisfactory manner.
The Board of Directors adopts annually rules of procedure for the work of the Board and
instructions for the division of work between the Board and the CEO. The rules of procedure
specify which matters require the approval or confirmation of the board. At the board meetings,
the CEO prefers matters that require the board's treatment.
The CEO shall ensure that the Board receives a factual, detailed and relevant information base
for the Board to be able to make well-informed decisions and that the Board is kept regularly
informed of the development of the company's operations and financial position.
Within IBT, internal control of financial reporting is focused, for example, on ensuring efficient
and reliable management and accounting of purchases and sales, other income accounting and
accounting of the company's financing. The internal control environment mainly comprises the
following five components: control environment, risk assessment, control activities, information
and communication and follow-up.
Control environment
In addition to the rules of procedure between the Board and the CEO, IBT's control structure is
based on the company's organization and ways of conducting operations where the roles and
responsibilities are defined and communicated in the organization. Employee awareness of
maintaining good control over financial reporting is satisfactory and analysis and follow-up of
62!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
financial progress is done monthly. Financial reports and compilations are made by IBT's
finance department and reported to the Board on a quarterly basis and to company
management on a monthly basis.
Risk assessment
The company works continuously with risk assessment and risk management to ensure that the
risks to which the company is exposed are managed within the framework that is ultimately
determined by the Board of Directors. The company management annually analyzes the
business processes of the business with regard to efficiency and risks. This work includes
identifying significant risks of errors in financial reporting and ensuring that there are appropriate
processes and controls within the business to manage these risks. Processes that are
considered to be of particular importance to IBT are research and development. A more detailed
description of the risk exposure can be found in the annual report.
Control activities
The risks identified in financial reporting are managed through a number of control measures in
the business processes. Processes, policies and controls are reviewed and updated annually.
The purpose is to detect, prevent and correct errors and deviations. The control structure also
includes, among other things, established powers (e.g. attestation), division of work, IT risks
and the management's monthly review of financial information. The company controls the
subcontractor's fulfillment of current services in accordance with agreements, including quality
aspects.
Information and communication
IBT has information and communication pathways aimed at promoting completeness and
accuracy in financial reporting. Certification procesures and communication policies are
distributed to all employees and kept available on the company's intranet. The entire company's
staff meet approx. once a month to increase knowledge of processes and objectives and to
exchange information and experience.
Evaluation
The company management annually evaluates internal control. The company's elected auditors,
Deloitte AB, also annually review a selection of IBT's routines and internal controls. The Board
then evaluates the information and ensures that measures are taken regarding the deficiencies
and proposals that have emerged.
63!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
MANAGEMENT DURING 2024
Staffan Strömberg
CEO since 2013. Born 1967.
M.Sc. in Chemical Engineering and Ph.D. in Organic Chemistry from the Royal Institute of
Technology in Stockholm.
Staffan Strömberg has more than 20 years of experience in the pharmaceutical industry.
Besides his roles at Billerud Tenova Bioplastics and at the Swedish Medical Products Agency,
he has also been Vice President of NIcOx France, had various project management positions
in AstraZeneca and been Head of R&D of Swedish Orphan. Board member of Eteboxagu AB
and BioGaia Pharma AB
Former CEO of Billerud Tenova Bioplastics AB and Head of Medical Devices at the Swedish
Medical Products Agency.
Shareholding in the Company: 51,873 series B-shares and 55,037 series B-shares through the
wholly owned company Eteboxagu AB and 120,000 warrants 2022/2025, 50,000 warrants
2023/2026 and 50,000 warrants 2024/2027.
Anders Kronström
Chief Operating Officer since 2018. Born 1967.
M.Sc., M.B.A.
Anders Kronström has over 25 years of experience working in the pharmaceutical industry. His
experience spans across all stages of drug development in different disease segments. During
his career at AstraZeneca he has had senior leadership positions within Project Management
and Business Development. More recently, he was a CEO of Biosergen AS, a Norwegian
biotechnology company.
Shareholding in the Company: 11,194 shares of series B and 75,000 warrants 2022/2025,
25,000 warrants 2023/2026 and 25,000 warrants 2024/2027.
Maria Ekdahl
Chief Financial Officer since 2022. Born 1973.
Master of Business Administration.
Maria has several years of financial background in both accounting and business controlling.
She has experience in various organizations such as Coca-Cola, Telenor, Karolinska Hospital
and the Swedish Film Institute.
Shareholding in the company: 3,452 shares of series B and 25,000 warrants 2023/2026 and
25,000 warrants 2024/2027.
64!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
BOARD OF DIRECTORS
IBT’s Board of Directors consists of five ordinary members, including the Chairman of the
Board, with no deputy board members, all of whom are elected for the period up until the end
of the annual shareholders’ meeting 2024S.
Peter Rothschild
Chairman of the Board since 2011. Born 1950.
Master of Business Administration from Stockholm School of Economics.
Founder and Chairman of the Board of Directors of BioGaia AB, BioGaia Pharma AB and
Annwall & Rothschild Investments AB. Board member of Allbright.
Previously CEO of BioGaia (publ) and member of the Board of Directors of Moberg Pharma AB
(publ).
Shareholding in the Company: 453,283 series A shares and 721,351 series B shares through
Annwall & Rothschild Investments AB, a company co-owned with Jan Annwall.
Margareta Hagman
Board member since 2015. Born 1966.
Master of Business Administration, Örebro University.
Since August 2024 CFO at Isofol Medical AB.
Previous positions: CFO and Deputy CEO of BioGaia AB (publ), and board member of BioGaia
Production AB, CapAble AB and Annwall & Rothschild Investments AB. Has also been active
as an advisor and consultant in Economics, Accounting and Finance.
Shareholding in the Company: 5,284 series B shares.
Eva Idén
Board member since 2017. Born 1966.
Civil Engineer in Chemistry, Chalmers Tekniska Högskola.
Consultant in leadership and organizational development and within the framework of that
business owner of Better & Beyond AB and partner and Chairman of Board in Inflecto AB.
Shareholding in the company: 560 series B shares.
65!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Anthon Jahreskog
Board member since 2017. Born 1980.
Candidate degree in Management and systems, City University, London. Bachelor of Business
Administration, Master of Science in Financial Management at University of Cape Town.
Board member of BioGaia AB (publ) and Fast Track Holdings Ltd.
Shareholding in the company: 24,270 series B shares.
Kristina Sjöblom Nygren
Board member since 2018. Born1961.
Kristina has received a Doctor of Medical Sciences from Karolinska Institutet and is a licensed
physician.
She is Chief Medical Officer, Head of Clinical Development, since May 2021 at Egetis
Therapeutics AB (publ) in Stockholm.
Kristina has extensive experience from the pharmaceutical industry, where she has held
among other positions Chief Medical Officer, Head Development at Santhera Pharmaceuticals
in Basel and Head of Clinical Development at SOBI in Stockholm.
Shareholding in the company: 100 series B shares.
66!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
The auditor’s examination of the corporate governance statement
To the general meeting of the shareholders in Infant Bacterial Therapeutics AB (publ)
corporate identity number 556873-8586
Engagement and responsibility
It is the board of directors who is responsible for the corporate governance statement for the
financial year 2024-01-01 - 2024-12-31 on pages 53-65 and that it has been prepared in
accordance with the Annual Accounts Act.
The scope of the audit
Our examination has been conducted in accordance with FAR’s standard RevR 16 The
auditor’s examination of the corporate governance statement. This means that our
examination of the corporate governance statement is different and substantially less in scope
than an audit conducted in accordance with International Standards on Auditing and generally
accepted auditing standards in Sweden. We believe that the examination has provided us with
sufficient basis for our opinions.
Opinions
A corporate governance statement has been prepared. Disclosures in accordance with
chapter 6 section 6 the second paragraph points 2-6 the Annual Accounts Act and chapter 7
section 31 the second paragraph the same law are consistent with the annual accounts and
the consolidated accounts and are in accordance with the Annual Accounts Act.
Stockholm 26 March 2025
Deloitte AB
Jenny Holmgren
Authorized Public Accountant
67!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
DEDUCTION OF CERTAIN KEY FIGURES
2024
Jan-Dec
2023
Jan-Dec
Cash flow per share
Cash flow for the period, 000's
-111,120
-4,704
Average number of shares
13,471,420
12,364,614
Cash flow per share (SEK)
-8.25
-0.38
Equity per share
Equity, 000's
170,263
305,154
Number of shares at end of period
13,471,420
13,471,420
Equity per share (SEK)
12.64
22.65
Equity ratio
Equity, 000's
170,263
305,154
Total equity and liabilities, 000's
239,566
351,334
Equity ratio %
71%
87%
SHARES AND OWNERSHIP STRUCTURE
As of January 1, 2024, the total number of shares amounted to 13,471,420 of which
453,283 A-shares with voting rights of 10 and 13,018,137 B-shares with voting rights of 1.
Infant Bacterial Therapeutics AB's series B-shares are listed on Nasdaq Stockholm since
September 10, 2018.
The number of shareholders was 5,222 on December 31, 2024 according to Euroclear
Sweden compared to 5,367 on December 31, 2023.
Share price development
IBT´s share price decreased from 90.00 SEK to 54.00 SEK during 2024. Market value as of
December 31, 2024 amounted to 727 MSEK.
Analysts covering IBT:
SEB: Christopher W. Uhde, PhD, Carl Mellerby, Mattias Vadsten
68!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Ownership December 31, 2024
Name
Class
A-shares
Class
B-shares
Share
capital %
Votes
%
ANNWALL & ROTHSCHILD INVESTMENT AB
453,283
721,351
8.72
29.93
SIX SIS AG, W8IMY
-
1,515,579
11.25
8.64
NORTHERN TRUST COMPANY
-
1,497,162
11.11
8.53
FJÄRDE AP-FONDEN
-
1,344,000
9.98
7.66
ÅLANDSBANKEN
-
436,172
3.24
2.49
AVANZA PENSION
-
372,309
2.76
2.12
DAVID DANGOOR
-
370,455
2.75
2.11
IBKR FINANCIAL SERVICES AG
-
343,432
2.55
1.96
P.R BANQUE PIXTET & CIE SA
-
311,169
2.31
1.77
NORDNET PENSIONSFÖRSÄKRING AB
-
243,315
1.81
1.39
Total 10 largest shareholders
453,283
7,154.944
56.48
66.61
Other shareholders
-
5,863,193
43.52
33.39
Total
453,283
13,018,137
100.00
100.00
Source: Euroclear Sweden
69!
Infant Bacterial Therapeutics AB
(publ)
Annual Report 2024
Contact Persons
Staffan Strömberg, CEO
Maria Ekdahl, CFO
Contact Information
Infant Bacterial Therapeutics AB (Reg. no. 556873-8586) Bryggargatan 10
111 21 Stockholm, Sweden
Email: [email protected]
www.ibtherapeutics.com